Table 1 Median values, 25% and 75% percentiles, mean of difference and standard deviation (SD) of concentrations of the thyroid gland hormones: thyroxin (T4), free thyroxin (fT4) and thyroid stimulating hormone (TSH), the secondary hemostatic markers: activated partial thrombin time (aPTT), prothrombin time (PT), fibrinogen, von Willebrand factor (vWf), d-dimer and thromboelastography parameters: reaction time (R), split point (SP), angle (α) and maximal amplitude (MA), platelet numbers (Plt) and C-reactive protein (CRP) measured in 20 sled dogs when they were untrained, trained for 4 months and trained for 4 months and had performed a 68 km run
| Â | Untrained | Â | Â | Â | Trained | Â | Â | Â | Trained | Â |
|---|---|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | Â | Â | 4Â months | Â | Â | Â | 4Â months | Â |
| Â | Â | Â | Â | Â | Â | Â | Â | Â | + 68Â km run | Â |
|  | Median | 25%; 75% | Mean of diff ± SD | Median [25%; 75%]†| Median | 25%; 75% | Mean of diff ± SD | Median [25%; 75%]†| Median | 25%; 75% |
| Â | Â | (percentiles) | Â | (percentiles) | Â | (percentiles) | (percentiles) | Â | (percentiles) | |
T4 (nmol/L) | 22.7 | 18.5;29.3 | -5.46 ± 8.2** |  | 17.4 | 13.7;21.0 | -6.11 ± 5.1*** |  | 8.7 | 6.8;15.6 |
fT4 (pmol/L) | 13.8 | 12.2;17.1 | -1.88 ± 3.2* |  | 12.6 | 10.5;14.6 | -2.05 ± 2.4** |  | 9.5 | 7.9;13.1 |
TSH (ng/mL) | 0.16 | 0.13;0.26 | -0.06 ± 0.1** |  | 0.11 | 0.08;0.16 |  | -0.02 [-0.07;0.01]** | 0.07 | 0.04;0.11 |
aPTT (sec) | 10.3 | 10.1;10.7 | -0.5 ± 0.5** |  | 9.85 | 9.6;10.2 | 0.02 ± 0.2 |  | 9.95 | 9.4;10.3 |
PT (sec) | 6.5 | 6.2;6.8 | 0.19 ± 0.3** |  | 6.7 | 6.4;6.9 |  | 0.3 [0.2;0.5]*** | 6.95 | 6.7;7.4 |
fibrinogen (g/L) | 2.74 | 2.4;3.4 |  | -0.2 [-0.7;-0.06]** | 2.48 | 2.2;2.7 | -0.17 ± 0.2** |  | 2.32 | 2.2;2.4 |
vWf (%) | 104.0 | 93;116 | 0.7 ± 17.8 |  | 98.3 | 87;116.9 | 20.26 ± 14.0*** |  | 124.5 | 110.9;135.1 |
d-dimer (mg/L) | 0.1 | 0.1;0.2 | Â | Â | 0.1 | 0.1;0.1 | Â | Â | Â | Â |
R (min) | 3.95 | 3.5;4.6 | 0.31 ± 1.48 |  | 4.14 | 3.6;5.5 |  | -1.1 [-1.9;-0.8]*** | 3.05 | 2.8;3.3 |
SP (min) | 3.35 | 3.0;3.8 | 0.47 ± 1.28 |  | 3.7 | 3.2;4.7 |  | -0.9 [-1.4;-0.65]*** | 2.8 | 2.5;3.1 |
α (degree) | 58.4 | 42.6;65.2 | 1.61 ± 16.7 |  | 59.1 | 40.3;66.4 | 12.6 ± 12.0** |  | 70.1 | 65.6;73.8 |
MA (mm) | 24.75 | 21.4;28.0 | -3.87 ± 3.9** |  | 20.00 | 18.6;23.2 | -1.8 ± 2.2** |  | 18.85 | 17.1;20.9 |
Plt (109/L) | 424 | 338;456 | -25.6 ± 87.4 |  | 375 | 315;438 | 2.4 ± 67.8 |  | 354 | 316;428 |
CRP (mg/L) | 2.0 | 0.9;9.75 | -2.2 ± 16.63 |  | 3.35 | 0.85;8.7 | 11.03 ± 9.09*** |  | 16.35 | 8.1;27.9 |