Table 4 Results of the one-way analysis of covariance and pairwise t-tests of the intra breed comparison

Variable	Group	Adjusted means (at BW = 8.36)	Equality of the adjusted means ( P-value)	Global regression coefficient		Equalitiy of regression coefficients
Variable	Group	Adjusted means (at BW = 8.36)	Equality of the adjusted means ( P-value)	Estimate	P-value	Estimates	P-value
Total brain volume	SM	79.02 ± 1.45	0.48	34.02 ± 7.93	< 0.001	44.28 ± 11.37	0.087
Total brain volume	No SM	77.50 ± 1.55				16.05 ± 9.60
Cerebral volume	SM	68.61 ± 1.50	0.42	26.19 ± 8.24	0.003	35.65 ± 11.68	0.130
Cerebral volume	No SM	66.78 ± 1.62				9.62 ± 10.61
Metencephalic volume	SM	10.99 ± 0.16	0.90	7.59 ± 0.90	< 0.001	7.99 ± 1.33	0.57
Metencephalic volume	No SM	11.02 ± 0.18				6.90 ± 1.16
Total endocranial volume	SM	83.02 ± 1.53	0.44	33.54 ± 8.40	< 0.001	40.45 ± 12.53	0.28
Total endocranial volume	No SM	81.25 ± 1.56				21.44 ± 9.91
Rostral and middle cranial fossa volume	SM	69.23 ± 1.62	0.95	23.33 ± 8.95	0.013	29.55 ± 13.15	0.37
Rostral and middle cranial fossa volume	No SM	69.09 ± 1.71				12.77 ± 11.47
Caudal cranial fossa volume	SM	11.98 ± 0.17	0.074	9.82 ± 0.96	< 0.001	9.92 ± 1.42	0.89
Caudal cranial fossa volume	No SM	12.53 ± 0.19				9.64 ± 1.22
Subarachnoid space	SM	4.31 ± 0.12	0.090	6.26 ± 0.67	< 0.001	6.87 ± 0.94	0.23
Subarachnoid space	No SM	3.99 ± 0.13				5.18 ± 0.92
Caudal fossa parenchyma percentage ^§	SM	0.89 ± 0.002	0.73	-0.0045 ± 0.00051	< 0.001	-0.0058 ± 0.00052	0.21
Caudal fossa parenchyma percentage ^§	No SM	0.89 ± 0.002				-0.0064 ± 0.00098

^§For the analysis of CFPP body weight was not transformed by logarithm.
The table presents the results of the comparison for Cavalier King Charles spaniels (CKCS) to test the equality of the regression coefficients (slopes) on the logarithm of the body weight (BW) and the equality of adjusted means at BW = 8.36 kg between the CKCSs with and without SM (SM). Significantly different estimates and p-values are bold-typed and represent the result of the pairwise comparison. Normal typed estimates and p-values are not significantly different and represent the result of the global comparison.

ISSN: 1751-0147