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Pulsatile administration of gonadotropin releasing hormone (Gn-RH) to lactating sows using a portable automatic pump (“Zyklomat”)

Pulsativ infusion av GnRH till digivande suggor med hjälp av en bärbar automatisk pump ( “Zyklomat”)

Abstract

The object of this investigation was to study the feasibility of using a “Zyklomat roller peristaltic pump” for pulsatile administration of gonadotropin releasing hormone (Gn-RH) in primiparous lactating sows. Four primiparous sows were used. The pump catheter was inserted into a jugular vein on day 8 or day 22 of lactation. The pump delivered a 1 min Gn-RH pulse of 10 μg every 89 min for 7 days. The pump worked without any complication or detrimental effect on the sows throughout the experimental period. Two sows showed standing oestrus during lactation and one of them ovulated. It can be concluded that the “Zyklomat” pump can be used for pulsatile infusion of Gn-RH in lactating sows.

Sammanfattning

Ändamålet med föreliggande undersökning var att fastställa om det är möjligt att tillföra Gn-RH till digivande ungsuggor med hjälp av en bärbar pump benämnd “Zyklomat roller peristaltic pump”. Fyra digivande ungsuggor an vändes i försöket. Katetern till pumpen place-rades i ena jugularvenen på dag 8 eller dag 22 av diperioden. Pumpen injicerade 10 μg GnRH under en minut var 89:e minut under 7 dagar. Pumpen fungerade utmärkt och suggorna visade inga tecken på oro eller besvär av att ha pumpen apterad på ryggen. Två suggor visade brunst med ståreflex under diperioden, en av dessa två ovulerade. Sammanfattningsvis visade denna studie att “Zyklomat”-pumpen är användbar för pulsativ infusion av Gn-RH till digivande suggor.

References

  • Bevers, M. M., A. H. Willemse, Th. A. M. Kruip & D. F. M. Van de Wiel: Prolactin levels and the LH-response to synthetic LH-RH in the lactating sow. Anim. Reprod, Sci. 1981, 4, 155–163.

    Article  CAS  Google Scholar 

  • Burger, J. F.: Sex physiology of pigs. Onderstepoort J. vet. Res. Suppl., 1952, 2, 3–218,

    Google Scholar 

  • Chambers, G. R., I. A. Sutherland, S. White, P. Mason & H. S. Jacobs: A new generation of pulsatile infusion devices. Uppsala J. med. Sci. 1984, 89, 91–95.

    Article  CAS  Google Scholar 

  • Cox, N. M. & J. H. Britt: Pulsatile administration of gonadotropin releasing hormone to lactating sows: Endocrine changes associated with induction of fertile estrus, Biol. Reprod. 1982, 27, 1126–1137.

    Article  CAS  Google Scholar 

  • Kirkwood, R. N., K. R. Lapwood, W. C. Smith & I. L. Anderson: Plasma concentration of LH, prolactin, oestradiol-17β and progesterone in sows weaned after lactation for 10 or 35 days. J. Reprod. Fert. 1984, 70, 95–102.

    Article  CAS  Google Scholar 

  • Kunavongkrit, A., S. Einarsson & I. Settergren: I. Follicular development in primiparous lactating sows. Anim. Reprod. Sci. 1982, 5, 47–56.

    Article  Google Scholar 

  • Kunavongkrit, A.: Clinical and endocrinological studies in primiparous post partum sows: Effect of lactation length and litter size. Acta vet. scand. 1984, 25, 260–279.

    CAS  PubMed  Google Scholar 

  • Leyendecker, G. & L. Wildt: Pulsatile administration of Gn-RH in hypothalamic amenorrhea. Uppsala J. med. Sci. 1984, 89, 19–32.

    Article  CAS  Google Scholar 

  • Rodriguez, H. & A. Kunavongkrit: Chronical venous catheterization for frequent blood sampling in unrestrained pigs. Acta vet. scand. 1983, 24, 318–320.

    CAS  PubMed  Google Scholar 

  • Schally, A. V., R. M. G. Nair, T. W. Redding & A. Arimura: Isolation of the luteinizing hormone and follicle stimulating hormone-releasing hormone from porcine hypothalami. J. biol. Chem. 1971, 246, 7230–7236.

    CAS  PubMed  Google Scholar 

  • Stevenson, J. S., N. M. Cox & J. H. Britt: Role of the ovary in controlling luteinizing hormone, follicle stimulating hormone, and prolactin secretion during and after lactation in pigs. Biol. Reprod. 1981, 24, 341–353.

    Article  CAS  Google Scholar 

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Rojanasthien, S., Kunavongkrit, A., Einarsson, S. et al. Pulsatile administration of gonadotropin releasing hormone (Gn-RH) to lactating sows using a portable automatic pump (“Zyklomat”). Acta Vet Scand 26, 442–448 (1985). https://doi.org/10.1186/BF03546516

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