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Barium Selenate: A Long-Acting Selenium Preparation for Subcutaneous Injection

Barium selenat: Et depotpreparat for subkutan injeksjon av selén

Abstract

Three flocks of sheep in typical selenium-deficient areas were injected with 2 ml Deposel® (100 mg selenium as barium selenate) in the autumn of 1982 and/or 1983. The selenium status in 10 ewes from each flock, and their offspring, was monitored by selenium analyses of blood samples. The injection induced an adequate increase in blood selenium within 8 weeks. Adequate selenium levels were maintained throughout the lambing season and the following summer. The selenium status in lambs from treated ewes was adequate until they were put out to pasture. Elevated selenium levels were maintained even throughout the next lambing season, and the second injection gave significantly higher blood selenium as compared to the first. The present preparation seems to be suitable and safe for protecting sheep against selenium deficiency. The dosage used seems sufficient to maintain an adequate selenium status for as long as 2 consecutive lambing seasons.

Sammendrag

Et preparat av barium selenat (Deposel®, Rycovet Ltd, Glasgow) for S.C. injeksjon ble utprøvd i 3 besetninger i typiske lavselénområder. Søyene ble injisert om høsten med en dose som tilsvarte 100 mg selén. En av besetningene ble også behandlet det påfølgende år. Ti søyer og deres lam ble fulgt med selénanalyser av blodprøver. En tilstrekkelig økning av blodselénnivået ble oppnådd innen 8 uker, og dette nivået holdt seg gjennom lammesesongen, den påfølgende sommer og fram til neste lammesesong. Lammene hadde tilstrekkelige nivåer av blodselén fram til beiteslipp. Gjentatt injeksjon med ett års mellomrom ga tydelig høyere selénnivåer enn første injeksjon. Det anvendte preparat synes vel egnet til å forebygge selénmangel hos sau. Den anvendte dose synes tilstrekkelig til å dekke behovet inntil 2 lammesesonger.

References

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Øvernes, G., Moksnes, K. & Frøslie, A. Barium Selenate: A Long-Acting Selenium Preparation for Subcutaneous Injection. Acta Vet Scand 26, 164–168 (1985). https://doi.org/10.1186/BF03546548

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