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Colostral Trypsin-Inhibitor Capacity in Different Animal Species
Trypsin-inhiberande kapacitet av kolostrum hos olika djurslag
Acta Veterinaria Scandinavica volume 20, pages 469–476 (1979)
Abstract
Colostral trypsin-inhibitor capacity was monitored during the first two weeks from parturition. The colostrum of the mare, sow, cow and ewe showed high antitrypsin activity at parturition, decreasing to about one hundredth during the first week. Canine milk remained on a relatively high antitrypsin level, and human milk was poor in antitrypsin from childbirth. The antitrypsin content seems to parallel the known changes in the colostral immunoglobulin levels of different species. The role of antitrypsin in protection of immunoglobulins from proteolytic damage during passive transfer of immunity to the newborn is obvious.
Sammanfattning
Kolostrum av sto, sugga, ko och tacka innehöll en hög trypsinhämmande kapacitet efter förlossningen. Aktiviteten sjönk till cirka en hundrade del under första veckan. Kolostrum från tikar innehöll en längre tid en högre antitrypsinaktivitet, men däremot är aktiviteten i modersmjölken låg redan från början.
Antitrypsinaktiviteten tycks följa immunoglobulinmängden. Antitrypsinet kan tänkas skydda immunoglobulinerna från proteolys under den passiva intestinala transporten av immunoglobulinerna till det nyfödda djuret.
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Sandholm, M., Honkanen-Buzalski, T. Colostral Trypsin-Inhibitor Capacity in Different Animal Species. Acta Vet Scand 20, 469–476 (1979). https://doi.org/10.1186/BF03546574
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DOI: https://doi.org/10.1186/BF03546574