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The Distribution of Cadmium Between Cellular Subfractions in Cadmium-Sensitive and Cadmium-Resistant Staphylococcus Aureus
Distributionen av kadmium mellan bakteriecellens subtraktioner i kadmiumkänslig och kadmiumresistent Staphylococcus aureus
Acta Veterinaria Scandinavica volume 20, pages 438–446 (1979)
Abstract
The accumulation and distribution of cadmium (Cd) between cellular subfractions were studied in Cd-resistant Staphylococcus 3719 + and its plasmid-negative Cd-sensitive variant 3719–, grown in media containing 0.01, 0.1 or 50 mg of Cd/litre. In the media containing 0.01 and 0.1 mg of Cd/1 the uptake of Cd by the Gd-resistant S. aureus was significantly less than that by Cd-sensitive S. aureus, both in toto and in terms of the cell wall fractions. Only variant 3719 + grew in the medium containing 50 mg of Cd/1. The finding of a lag phase in the growth of both variants is interpreted to suggest that the resistance is of inducible character, even in the sensitive S. aureus. The mechanism of resistance to Cd could consist of both barrier and clearance functions.
Sammanfattning
Ackumulationen och distributionen av kadmium (Cd) mellan bakteriecellens subfraktioner undersöktes på en Cd-resistent Staphylococcus aureus 3719 + och des-s plasmid-negativa, Cd-känsliga variant 3719— i medier som innehöll 0,01, 0,1 eller 50 mg Cd/liter. I medier som innehöll 0,01 eller 0,1 mg Cd/1 var både det totala upptaget av Cd och ackumulationen av Cd i cellväggen signifikant större hos den Cd-känsliga än hos den Cd-resistenta varianten. Endast den Cd-resistenta varianten växte i mediet, som innehöll 50 mg Cd/1. Förekomst av lagfas under växten vid bagge varianterna ansågs som ett bevis för den inducerbara karaktaren av resistensen även på den Cd-känsliga S. aureus. De undersökta bakteriernas resistens mot Cd ansågs kunna bestå av både barriär- och eliminationsfunktioner.
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Korkeala, H. The Distribution of Cadmium Between Cellular Subfractions in Cadmium-Sensitive and Cadmium-Resistant Staphylococcus Aureus. Acta Vet Scand 20, 438–446 (1979). https://doi.org/10.1186/BF03546605
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DOI: https://doi.org/10.1186/BF03546605