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Exogenous Prostaglandin F2α Promotes Uterine Involution in the Cow
Exogent prostaglandin F2α forkortar tiden för livmoderinvolutionen hos ko
Acta Veterinaria Scandinavica volume 24, pages 269–274 (1983)
Abstract
Three newly delivered dairy cows were given prostaglandin F2α during the immediate postpartum period. PGF2α was administered from day 3–13 post partum in doses of 25 mg twice daily. Endogenous release of PGF2α and progesterone was studied in blood plasma during the experimental period. Rectal examination of the uterus was performed every second day in order to establish the end of uterine involution. Uterine involution in the three cows was completed days 16, 23 and 20, respectively. These figures are to be compared with earlier investigations of uterine involution times, which show about 27 days. It was concluded that PGF2α had a positive effect on the uterine muscular tone.
Sammanfattning
Under senare ør har visais att livmiodern hos ko producerar stora mängder prostaglandin F2α under förlossningen samt under en period på mellan 2 till 3 veckor därefter. Vidare har visais ett sam-band mellan duration-en av denna prostaglandinfrisättning och tiden for livmoderns involution. Ju längre tid efter förlossningen som prostaglandin frisättes ju snabbare sker involutionen. I föreliggande un-dersökning har 3 nykalvade kvigor behandlats med PGF2α under tiden 3–13 dagar efter förlossningen. Dosen har varit 25 mg och djuren har behandlats med denna dos två gånger dagligen. Rektal-undersökning har utförts var annan dag för fastställande av tidpunk-ten när livmoderinvolutionen är avslutad. Resultaten visade att liv-modern hos de 3 kvigorna var helt återbildad efter respektive 16, 23 och 20 dagar. Detta är en förkortning av tiden jämfört med tidigare undersökningar vilka visar i genomsnitt oa 27 dagar.
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Lindell, JO., Kindahl, H. Exogenous Prostaglandin F2α Promotes Uterine Involution in the Cow. Acta Vet Scand 24, 269–274 (1983). https://doi.org/10.1186/BF03546730
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DOI: https://doi.org/10.1186/BF03546730