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Spontaneous Aortic Lesions in Roe Deer (Capreolus Capreolus L)

Spontana aortaskador hos rådjur (Capreolus capreolus L)

Acta Veterinaria Scandinavica volume 24, pages 153–169 (1983)Cite this article

Abstract

In 34 out of 60 aortas from roe deer, aged from 6 months to more than 8 years, aortic lesions were found. The frequency of affected regions involved were, in the posterior abdominal portion 53.3 %, in the aortic arch 18.3 %, in the anterior abdominal portion 16.7 %, in the posterior thoracic portion 8.33 % and in the anterior thoracic portion 3.3 %. Of the observed lesions, fatty streaks were seen in 3, fatty streaks and fibrous plaques in 3, fatty streaks with complicated lesions (calcification and acid mucopolysaccharides) in 14 and fibrous plaques with complicated lesions in 14 of the aortas. Elastic tissue degeneration of the inner two thirds of the tunica media was principally found in the aorta of the animals beyond 4 years of age. The lesions significantly (P < 0.001) increased in number and severity with age and appeared to be more progressive in pregnant animals. There was, however, no significant difference between affected male and female animals in the different age groups.

Sammanfattning

Hos 34 av 60 undersökta rådjur, 6 månader — äldre än 8 år, före-låg aortaskador. Frekvensen skadade regioner var: bakre abdominala delen 53,3 %, aortabågen 18,3 %, främre abdominala delen 16,7 %, bakre törakala den 8,3 % och främre torakala delen 3,3 %. Stråk av fett förelag hos 3, stråk av fett och fibrösia knutor hos 3, stråk av fett med komplicerade skador (förkalkningar och sura mucopolysacca-rider) hos 14 och fibrösa knutor med komplicerade skador hos 14. Degeneration av elastisk vävnad i de inre 2/3 av tunica media förelåg huvudsakligen i aortor hos djur äldre än 4 år. Skadorna ökade signifikant i ant al och svårighetsgrad med åider med en tendens till mer utbredda skador hos dräktiga djur. Det förelåg emellertid ingen signifikant skillnad mellan hon- och handjur i olika åldersgrupper.

References

  • Andersen, J.: Analysis of a Danish roe deer population. In: Analysis of Danish review of game biology. Ed. by Spärck, R. and H. M. J. H. Thamrup. Vol. II. Schulz Publisher, Copenhagen 1953, pp. 131–153.

  • Borg, K.: On mortality and reproduction of roe deer in Sweden during the period 1948–1969. Swedish Wildlife 1970, 7, 121–149.

    Google Scholar 

  • Carlson, L. A., I. Erikson & G. Walldius: A case of massive hypertri-glyceridaemia and impair fatty acid incorporation into adipose tissue glycerides (FIAT) both corrected by nicotinic acid. Acta med. scand. 1973a, 194, 363–369.

  • Carlson, L. A., G. Walldius & A. G. Olsson: Evidence for a defect in fatty acid uptake by adipose tissue of patient with hypertri-glyceridaemia. J. clin. Path. 26. suppl. 1973b, 5, 48–52.

  • Clarke, J. A.: An X-ray microscopic study of the vasa vasorum of normal human coronary arteries. J. Anat. (Lond.) 1964, 98, 539–543.

    CAS  Google Scholar 

  • Clarke, J. A.: An X-ray microscopic study of the postnatal development of the vasa vasorum in the human aorta. J. Anat. (Lond.) 1965a, 99, 887–889.

  • Clarke, J. A.: The vasa vasorum or normal human lower limb arteries. Acta anat. (Basel). 1965b, 61, 481–487.

  • De Faria, J. L.: Role of medial change in the pathogenesis of the intimai thickening and in atherosclerosis. J. Atheroscler. Res. 1965, 5, 509–515.

    Article  Google Scholar 

  • Drozdz, A. & A. Osiecki: Intake and digestibility of natural feed by roe deer. Acta theriol. 1973, 18, 81–91.

    Article  Google Scholar 

  • Esterley, J. A. S. Glagou: Altered permeability of the renal of the hypertension rat. An electron microscopy study. Amer. J. Path. 1963, 43, 619–631.

    Google Scholar 

  • Gaton, E. & M. Wolman: The role of smooth muscle cells and hematogenous mocrophage in atheroma. J. Path. 1977, 123, 123–125.

    Article  CAS  Google Scholar 

  • Gerrity, R. G., H. K. Natio, M. Richardson & C. J. Schwartz: Dietary induced atherogenesis in swine. Amer. J. Path. 1979, 95, 775–785.

  • Gerrity, R. G.: The role of the monocyte in atherogenesis. Amer. J. Path. 1981, 103, 181–260.

    CAS  PubMed  Google Scholar 

  • Glagov, S.: Hemodynamic factors in localization of atherosclerosis. Acta cardiol. Suppl. 11. 1965, 11, 311–337.

    Google Scholar 

  • Gupta, P. P. & B. Singh: Natural occurring atherosclerotic lesions and aging change in the aorta of Indian water buffaloes (Bubalus bubalus). Zbl. Vet.-Med. A. 1978, 25, 231–240.

    Article  CAS  Google Scholar 

  • Gupta, P. P. & C. Rehbinder: Spontaneous aortic lesions in reindeer. Acta vet. scand. 1981, 22, 60–66.

    CAS  PubMed  Google Scholar 

  • Halberg, D.: Elimination of exogenous lipid from the blood stream. An experimental methodological and clinical study in dog and man. Acta physiol. scand. 65. suppl. 1965, 254, 1–23.

    Google Scholar 

  • Holman, R. L., H. C. McGill, J. F. Strong & J. C. Geer: The natural history of atherosclerosis (The early aortic lesions as seen in New Orleans in the middle of the 20th century). Amer. J. Path. 1958, 34, 209–235.

    CAS  PubMed  Google Scholar 

  • Jönsson, L.: Coronary lesions and myocardial infarct in the dog. Acta vet. scand. Suppl. 1972, 38, 1–80.

    PubMed  Google Scholar 

  • Korn, E. D.: Clearing factor, a heparin activated lipoprotein lipase. I. Isolation and characterization of the enzyme from normal rat heart. J. biol. Chem. 1955, 215, 1–14.

    CAS  PubMed  Google Scholar 

  • Korn, E. D. & J. W. Quigley: Studies on lipoprotein lipase of rat heart and adipose tissue. Biochim. biophys. Acta (Amst.). 1955, 18, 143–145.

    Article  CAS  Google Scholar 

  • Lansing, A. I., E. Roberts, G. B. Ramasama, T. B. Rosenthal & M. Alex: Change with age in amino acid composition of arterial elastin. Proc. Soc. exp. Biol. Med. (N.Y.). 1951, 76, 714–717.

  • Moskowitz, M. S. & A. A. Moskowitz: Lipase localization in adipose tissue. Science 1965, 149, 72–73.

    Article  CAS  Google Scholar 

  • Mustard, J. F. & M. A. Packham: Factor influencing function adhesion, release, and aggregation. Pharmac. Rev. 1970, 22, 97–187.

    CAS  Google Scholar 

  • Okawa, H., K. Doi, A. Yasoshima, T. Fugita & A. Okaniwa: Pathology of experimental atherosclerosis, change of acute phase in rats loaded with vitamin D2 and cholesterole. Jap. J. vet. Sci. 1980, 42, 623–633.

    Article  CAS  Google Scholar 

  • Paterson, J. C., J. Mille & T. Moffat: Vascularization of early atherosclerotic plaques, Archs. Path. 1957, 64, 129–136.

    CAS  Google Scholar 

  • Prasad, M. C., B. S. Rajya & G. C. Mohanty: Study on lipid pattern and protein content of caprine aortic atherosclerosis. Indian J. vet. Sci. 1976, 46, 179–183.

    CAS  Google Scholar 

  • Radomski, M. W. & T. Orme: Response of lipoprotein lipase in various tissue to cold exposure. Amer. J. Physiol. 1971, 220, 1852–1856.

    Article  CAS  Google Scholar 

  • Rehbinder, C. & P. Ciszuk: Supplementary feeding of roe deer (Ca-preolus capreolus) with late harvest hay. A pilot study. J. Wildl. Manage. 1983, in press.

  • Robertson, O. H., B. C. Wexler & F. B. Miller: Deneration changes in the en do vascular system of Pacific salmon (Oncornynchus tshawytscha). Circulation Res, 1961, 9, 826–834.

    Article  CAS  Google Scholar 

  • Roger, M. P. & D. S. Robinson: Effect of cold exposure on heart clearing factor lipase and triglyceride utilization in the rat. J. Lipid Res, 1974, 15, 263–272.

    Google Scholar 

  • Ross, R. & J. A. Glomset: Medical progress. The pathogenesis of atherosclerosis. New Engl. J. Med. 1976, 395, 369–377, 420–425.

  • Sako, Y.: Effect of turbulent flow and hypertension on experimental atherosclerosis. J. Amer. med. Ass. 1962, 119, 36–40.

    Article  Google Scholar 

  • Schnatz, J. D., J. W. Ormsby & R. H. Williams: Lipoprotein lipase activity in human heart. Amer. J. Physiol. 1963, 205, 401–400.

    Article  CAS  Google Scholar 

  • Skold, B. H., N. L. Jacobson & R. Getty: Spontaneous atherosclerosis of bovine. J. Dairy Sci. 1967, 50, 1712.

    Article  CAS  Google Scholar 

  • Texton, M., A. M. Imparato & M. Helpern: The role of vascular dynamic in the development of atherosclerosis. J. Amer. med. Ass. 1965, 149, 168–172.

    Google Scholar 

  • Valtonen, M. H. & A. Oksanen: Cardiovascular disease and nephritis in dog. J. small Anim. Pract. 1972, 13, 687–697.

    Article  CAS  Google Scholar 

  • Westake, G. E., S. M. Grundy & R. M. O’Neal: The effect of an atherogenic diet on preexisting aorta intimai thickening in old dog. Exp. Molecul. Pathol. 2. Suppl. 1963, 1, 1–8.

    Google Scholar 

  • Wilens, S. L.: The resorption of arterial atheromatous deposits in wasting disease. Amer. J. Path. 1951a, 23, 793–804.

  • Wilens, S. L.: Experimental of lipid deposition in existed arteries. Science 1951b, 114, 389–393.

  • Wigger, K. D., N. L. Jacobson & R. Getty: Atherosclerosis in ruminants. J. Anim. Sci. 1971, 32, 1037–1041.

    Article  Google Scholar 

  • Wissler, R. W. & D. Vesselinovitch: Atherosclerosis in non human primates. Adv. Vet. Sci. Comp. Med. 1977, 21, 351–361.

    CAS  PubMed  Google Scholar 

  • WHO Study Group on Atherosclerosis: Classification of atherosclerotic lesions. Tech. Rep. Ser. Wld. Hlth. Org. No. 143, WHO, Geneva 1958, p. 1–22.

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  1. Department of Pathology, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, S-750 07, Uppsala, Sweden

    Somlak Poungshompoo & Claes Rehbinder

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  1. Somlak Poungshompoo
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  2. Claes Rehbinder
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Poungshompoo, S., Rehbinder, C. Spontaneous Aortic Lesions in Roe Deer (Capreolus Capreolus L). Acta Vet Scand 24, 153–169 (1983). https://doi.org/10.1186/BF03546744

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Acta Veterinaria Scandinavica

ISSN: 1751-0147