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Antibodies to Corynebacterium Pseudotuberculosis in Adult Goats from a Naturally Infected Herd
Antistoffer mot Corynebacterium pseudotuberculosis hos voksne geiter fra en naturlig smittet besetning.
Acta Veterinaria Scandinavica volume 23, pages 473–482 (1982)
Abstract
Serum samples taken in 3 successive years (1977, 1978 and 1979) from adult dairy goats (Norwegian breed) originating from 1 herd were examined for antibodies to Gorynebacterium pseudotuberculosis. Both bacterial agglutination test (BAT) and hemolysis inhibition test (HIT) were used. The proportion of seropositive goats increased 10–12 % during the investigation period. In 1979 all animals were seropositive to BAT and about 95 % had antihemolysins in their sera. Twenty-two of the 23 one-year old goats recruited to the herd in 1978 were seropositive. The average age-specific titres increased up to the age of 3 years, and subsequently decreased for goats aged 4–7 years. Caseous lymphadenitis is thus regarded as a chronic infection. The effect of age on the titre values was significant at the 5 % level in 1977 and 1978 when HIT was used and in 1978 when BAT was used. During the investigation period the same 36 and 40 goats were examined every year by BAT and HIT, respectively. Intermediate to high correlations between titre values for the same goats from year to year were found.
Both BAT and HIT are suitable for sero-epidemiological investigations concerning infection with G. pseudotuberculosis in goats.
Sammendrag
Serumprøver fra voksne geiter (norsk rase) i én besetning ble undersøkt 3 år på rad (1977, -78 og -79) for antistoffer mot Goryne-bacterium pseudotuberculosis. Både bakterieagglutinasjonstest (BAT) og antihemolysintest (AHT) ble benyttet. I løpet av undersøkelses-perioden økte andelen av seropositive geiter med 10–12 %. I 1979 var samtlige dyr seropositive i BAT, mens ca. 95 % hadde antihemo-lysiner i serum. Blant 1-års gamle geiter som ble rekrutiert til beset-ningen i 1978 var 22 av 23 seropositive. Gjennomsnittlig titerverdier i løpet av årene undersøkelsen varte, utregnet etter geitenes alder, økte opp til 3 års alder og avtok deretter hos 4–7 år gamle geiter. Kaseøs lymfadenitt betraktes således som en kronisk infeksjon. Effekten av alder på titerverdiene var signifikant (0,01 < Ρ < 0,05) i 1977 og 1978 (AHT) og i 1978 (BAT).
En gruppe på ca. 40 geiter ble undersøkt årlig i 3 år med både BAT og AHT. Det ble påvist middels høge til høge korrelasjoner mel-lom titerverdiene hos de samme dyra fra år til år.
Både BAT og AHT er egnet for sero-epidemiologiske undersøkel-ser vedrørende kaseøs lmfadenitt hos geit.
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This study was supported by grants from the Agricultural Research Council of Norway.
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Lund, A., Almlid, T., Larsen, H.J. et al. Antibodies to Corynebacterium Pseudotuberculosis in Adult Goats from a Naturally Infected Herd. Acta Vet Scand 23, 473–482 (1982). https://doi.org/10.1186/BF03546766
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DOI: https://doi.org/10.1186/BF03546766