Skip to main content
  • Published:

An Investigation of Ovine Pneumonia in Four Herds from Central Norway

En undersøkelse au ovin pneumoni i 4 besetninger fra midt-Norge. II. Relasjon mellom patomorfologiske forandringer og tilstedeværelsen av mikro-organismer

II. Relation Between Pathomorphology and Presence of Micro-Organisms

Abstract

Sheep lungs obtained at slaughter from 4 herds from Central Norway were subjected to a macroscopical examination. Gross pulmonary findings included normal lungs, fibrous pleurisy, verminous nodules, atelectasis and consolidations of lobular and lobar extensions. A selection of lungs representing the various gross findings was subjected to microbiological and histological examinations. Pleurisy was associated wtih pneumonic consolidations and extension of lesions. Verminous nodules indicative of Muellerius spp. migrations occurred irrespective of gross pulmonary lesions or microbiological findings. A subacute or chronic pneumonia of a mixed proliferative exudative type was demonstrated in consolidated tissue. An association was found between the isolation of Mycoplasma ovipneumoniae and the presence of pneumonic lesions and between the number of organisms and extension of lesions. Histological findings highly indicative of this organism were proliferative changes in the bronchiolar and bronchial epithelium and intrapulmonary lymphoid tissue. The intensity of these changes was correlated to the number of mycoplasma organisms present. Mycoplasma ovipneumoniae is suggested to be of primary etiological significance regarding subacute or chronic pneumonia in lambs at slaughter.

Sammendrag

Lunger fra samtlige dyr slaktet i 4 sauebesetninger ble undersøkt makroskopisk med henblikk på pneumoniske forandringer. De makroskopiske funn omfattet normale lunger, fibrøs pleuritt, lungeorm-knuter, atelektase samt pneumoniske fortetninger av lobulær og lobær utbredelse.

Et utvalg av lunger som representerte de ulike makroskopiske funn ble undersøkt naermere mikrobiologisk og histologisk. Det ble påvist sammenheng mellom pleuritt og pneumoni samt utbredelsen av pneumoniske lesjoner. Lungeorm-knuter som indikerte Muelleriusvandringer opptrådte uavhengig av andre makroskopiske forandringer eller mikrobiologiske funn. Det makroskopiske og histologiske bilde av pneumoniske fortetninger viste subakutte til kroniske betennelsesforandringer af en proliferativ eksudativ type. Det ble påvist sammenheng mellom pneumoniske fortetninger og tilstedevaerelsen av Mycoplasma ovipneumoniae samt utbredelsen av lesjoner og veksttiter. Proliferative forandringer i bronkiole- og bronkie-epitel såvel som i det intrapulmonale lymfoide vev ble funnet å vaere sterke indikasjoner for tilstedevaerelsen av M. ovipneumoniae. Videre ble det påvist sammenheng mellom intensiteten av histologiske forandringer og veksttiter. M. ovipneumoniae antas å vœre av primser etioolgisk betydning for subakutt eller kronisk pneumoni som finnes hos høstslaktede lam.

References

  • Alley, M. R.: The bacterial flora of the respiratory tract of normal and pneumonic sheep. N.Z. vet. J. 1975, 23, 113–118.

    Article  CAS  Google Scholar 

  • Alley, M. R. & J. K. Clarke: The experimental transmission of ovine chronic non-progressive pneumonia. N.Z. vet. J. 1979, 27, 217–220.

    Article  CAS  Google Scholar 

  • Alley, M. R. & J. K. Clarke: The effect of chemotherapeutic agents on the transmission of ovine chronic non-progressive pneumonia. N.Z. vet J. 1980, 28, 77–80.

    Article  CAS  Google Scholar 

  • Bakke, T.: The occurrence of mycoplasmas and bacteria in lungs from sheep in Southern Norway. Acta vet. scand. 1982, 23, 235–247.

    CAS  PubMed  Google Scholar 

  • Bakke, T. & S. Nøstvold: An investigation of ovine pneumonia in four herds from Central Norway. I. Prevalence of pneumonia and microbiological findings. Acta vet. scand. 1982, 23, 248–258.

    CAS  PubMed  Google Scholar 

  • Cate, C. C. & R. Burrel: Lung antigen induced cellmediated immune injury in chronic respiratory diseases. Amer. Rev. resp. Dis. 1974, 109, 114–123.

    CAS  PubMed  Google Scholar 

  • Denny, E. W., D. Taylor-Robinson & A. C. Allison: The role of thymus-dependent immunity in Mycoplasma pulmonis infections in mice. J. med. Microbiol. 1972, 5, 327–336.

    Article  CAS  Google Scholar 

  • Dysart, T. H.: Enzootic pneumonia – its effect on the meat industry. Proc. 6th seminar of the New Zealand Veterinary Association of Sheep Society 1976, p. 94–100.

  • Foggie, A., G. E. Jones & D. Buxton: The experimental infection of specific pathogen free lambs with Mycoplasma ovipneumoniae. Res. Vet. Sci. 1976, 21, 28–35.

    Article  CAS  Google Scholar 

  • Gilmour, J. S., G. E. Jones & A. G. Rae: Experimental studies of chronic pneumonia of sheep. Comp. Immun. Microbiol, infect. Dis. 1979, 1, 285–293.

    Article  CAS  Google Scholar 

  • Gilmour, N. J. L.; Pasteurellosis in sheep. Vet. Rec. 1978, 102, 100–102.

  • Jericho, K. W. F.: Interpretation of the histopathological changes of porcine enzootic pneumonia. Vet. Bull. 1977, 47, 887–889.

    Google Scholar 

  • Jones, G. E., J. S. Gilmour & A. Rae: Endobronchial inoculation of sheep with lung-tissue suspensions and with the bacteria and mycoplasmas isolated from them. J. comp. Path. 1978, 88, 85–96.

  • Jones, G. E., D. Buxton & D. B. Harker: Respiratory infections in housed sheep, with particular reference to mycoplasmas. Vet. Microbiol. 1979, 4, 47–59.

    Article  Google Scholar 

  • Jubb, K. V. F. & P. C. Kennedy: Pathology of Domestic Animals. Vol. 1. Academic Press, New York & London 1970, p. 260–262, 279.

  • Kirton, A. H., P. J. O’Hara, E. H. Shortridge & D. O. Cordes: Seasonal incidence of enzootic pneumonia and its effect of the growth of lambs. N.Z. vet. J. 1976, 24, 59–64.

    Article  CAS  Google Scholar 

  • McGodan, B., D. C. Thurley, K. D. McSporran & A. T. Pfeffer: Enzootic pneumonia-pleurisy complex in sheep and lambs. N.Z. vet. J. 1978, 26, 169–172.

    Article  Google Scholar 

  • McSporran, K. D. & A. Russel: Fibrinolytic activity of the ovine pleural mesothelium. N.Z.J, agric. Res. 1978, 21, 127–129.

    Article  CAS  Google Scholar 

  • Soulsby, E. J. L.: Helminths, Arthropods and Protozoa of Domesticated Animals. Sixth edition of Mönnig’s Veterinary Helminthology and Entomology, Ballière, Tindall and Cassel Ltd., London 1968, p. 261–262.

  • Stamp, J. T. & D. I. Nisbet: Pneumonia of sheep. J. comp. Path. 1963, 73, 319–338.

    Article  CAS  Google Scholar 

  • St. George, T. D., N. D. Sullivan, J. A. Love & N. Horsfall: Experimental transmission of pneumonia in sheep with a mycoplasma isolated from pneumonic sheep lung. Aust. vet. J. 1971, 47, 282–283.

    Article  Google Scholar 

  • St. George, T. D. & N. D. Sullivan: Pneumonias of sheep in Australia. Veterinary Review No. 13. Post-Graduate Foundation in Veterinary Science, University of Sydney 1973, 22 pp.

  • Sullivan, N. D., T. D. St. George & N. Horsfall: A proliferative interstitial pneumonia of sheep associated with mycoplasma infection. 1. Natural history of the disease in a flock. Aust. vet. J. 1973 a, 49, 57–62.

  • Sullivan, N. D., T. D. St. George & N. Horsfall: A proliferative interstitial pneumonia of sheep associated with mycoplasma infection. 2. The experimental exposure of young lambs to infection. Aust. vet. J. 1973 b, 49, 63–68.

  • Taylor-Robinson, D., F. W. Denny, A. S. Allison, G. W. Thomson & G. Taylor: Gellmediated immunity and the response to mycoplasma infections. In: Pathogenic Mycoplasmas, Ciba Foundation Symposium, Associated Scientific Publishers, Amsterdam 1972, p. 349–362.

Download references

Author information

Authors and Affiliations

Authors

Additional information

This work was supported by grants from the Norwegian Agricultural Research Council.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Nøstvold, S., Bakke, T. An Investigation of Ovine Pneumonia in Four Herds from Central Norway. Acta Vet Scand 23, 259–274 (1982). https://doi.org/10.1186/BF03546811

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1186/BF03546811

Keywords