- Published:
Pathology of Bovine Laminitis Especially As Regards Vascular Lesions
Patologin vid fång, hos nötkreatur med särskild hänsyn till kärlförändringar
Acta Veterinaria Scandinavica volume 21, pages 559–566 (1980)
Abstract
Macro- and microscopical changes in the hooves of 14 cattle having a clinically established diagnosis of laminitis are described, Deviation of the pedal bone was found in 10 of the animals. In acute laminitis, the microscopical changes in the corium were hyperaemia, oedema, thrombosis and haemorrhages. Degenerative changes were found in the epidermis especially in the vicinity of thromboses of vessels in the corium. In chronic laminitis, arteriolosclerosis and arteriosclerosis were constant findings in the corium. There was also a high frequency of chronic thrombi and chronic granulation tissue. Prominent features in the lamellae epidermales were hyper- and parakeratosis. As judged from changes in arterioles and arteries, hypertension is suggested to be a pathogenetic factor in bovine laminitis.
cattle; laminitis; histology; arteriolosclerosis; arteriosclerosis.
Sammanfattning
Makro- och mikroskopiska förändringar i klövarna från 14 nötkreatur med den kliniska diagnosen fång beskrivs. Klövbensrotation påvisades hos 10 djur. Vid akut fång sågs histologiskt i läderhuden hyperemi, ödem, tromboser och blödningar. Degenerativa förändringar i epidermis iakttogs särskilt markant i anslutning till tromboser i corium. Vid kronisk fång var arterioloscleros och arterioscleros ett genomgående fynd i corium. Kroniska tromber och kronisk granulationsvävnad var också vanligt förekommande. I lamellae epidermales var hyper- och parakeratosförändringar framträdande. På basis av förändringarna i arterioler och artärer bedöms hypertension vara en trolig faktor i patogenesen vid fång hos nötkreatur.
References
Andersson, L.: Frequency studies and clinical observations in bovine laminitis. Nord. Vet.-Med. 1980, 32, 301–307.
Cheville, N. F.: Cell Pathology. The Iowa State University Press, Ames 1976, 454–457.
Coffman, J. R., H. E. Garner, A. W. Hahn & J. Hartley: Characterization of refractory laiminitis. Proc. Amer. Ass. Equine Pract. 1972, 351–358.
Dougherty, R. W., K. S. Coburn, H. M. Cook & M. J. Allison: Preliminary study of appearance of endotoxin in circulatory system of sheep and cattle after induced grain engorgement. Amer. J. vet. Res. 1975, 36, 831–832.
Dunlop, R. H. & P. B. Hammond: D-lactic acidosis of ruminants. Ann. N.Y. Acad. Sci. 1960, 119, 1109–1131.
Garner, H. E., J. R. Coffman, A. W. Hahn, C. Salem & J. H. Johnson: Arterial pressure, cardiac output, plasma volume and L-lactate changes in equine laminitis. Physiologist 1975a, 18, 224.
Garner, H. E., J. R. Coffman, A. W. Hahn, D. P. Hutcheson & M. E. Tumbleson: Equine laiminitis of alimentary origin: An experimental model. Amer. J. vet. Res. 1975 b, 36, 441–444.
Garner, H. E., D. P. Hutcheson, J. R. Coffman, A. W. Hahn & C. Salem: Lactic acidosis: A factor associated with equine laminitis. J. Anim. Sci. 1977 a, 45, 1037–1041.
Garner, H. E., A. W. Hahn, C. Salem, J. R. Coffman, D. P. Hutcheson & J. H. Johnson: Cardiac output, left ventricular ejection rate, plasma volume and heart rate changes in equine laminitis – hypertension. Amer. J. vet. Res. 1977 b, 38, 725–729.
Garner, H. E., J. 2V. Moore, J. H. Johnson, L. Clark, J. F. Amend, L. G. Tritschler, J. R. Coffman, R. F. Sprouse, D. P. Hutcheson & C. A. Salem: Changes in the caecal flora associated with the onset of laminitis. Equine vet. J. 1978, 10, 249–252.
Greenough, P. R.: The nomenclature of anatomical features of the bovine digits. Rep. 2nd Symp. Bovine Digital Diseases, Skara, Sweden 1978, 15–24.
Maclean, C. W.: The histology of laminitis in dairy cows. J. comp. Path. 1971, 18, 563–570.
Moore, J. N., H. E. Garner, J. N. Berg & R. F. Sprouse: Intracecal endotoxin and lactate during the onset of equine laminitis: A preliminary report. Amer. J. vet. Res. 1979, 40, 722–723.
Nilsson, S. A.: Clinical, Morphological, and Experimental Studies of Laminitis in Cattle. Acta vet. scand. 1963, 4, Suppl. 1.
Obel, N.: Studies on the Histopathology of Acute Laminitis. Almquist & Wiksells Boktryckeri AB, Uppsala, Sweden 1948.
Peterse, D. J.: Judgement of Bovine Claws by the Occurrence of Sole Lesions. Thesis, Utrecht 1980.
Robbins, S. L.: Pathologic Basis of Disease. W. B. Saunders Book Company, Philadelphia, London, Toronto 1974, 602–604.
Rosenberger, G.: Krankheiten des Rindes. (Diseases of cattle). Verlag Paul Parey, Berlin und Hamburg 1978.
Tizard, J. R.: An Introduction to Veterinary Immunology. W. B. Saunders Book Company, Philadelphia, London, Toronto 1977, 297.
Àkerblom, E.: Über die Ätiologie und Pathogenese der Hufrehe beim Pferde. (On the aetiology and pathogenesis of equine alimentary laminitis). Skand. Arch. Physiol. 1934, 68, Suppl. 1.
Author information
Authors and Affiliations
Additional information
This investigation was supported by grants from the Swedish Council for Forestry and Agricultural Research.
Rights and permissions
About this article
Cite this article
Andersson, L., Bergman, A. Pathology of Bovine Laminitis Especially As Regards Vascular Lesions. Acta Vet Scand 21, 559–566 (1980). https://doi.org/10.1186/BF03546843
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1186/BF03546843