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Organ Distribution of Some Clinically Important Enzymes in Mink

Några kliniskt viktiga enzymers fördelning på olika organ hos mink

Abstract

The activity and relative distribution of eight clinically important enzymes were measured in nine different organs in 10 healthy minks. Of the enzymes studied, OCT, ASAT and ALAT had higher absolute activities when compared to many other animals. This is believed to be adaptation to a high protein diet. OCT shows absolute liver specificity, and even ALAT is relatively liver specific in mink. SDH is found in relatively high concentrations in the liver as well as in the kidney. The organ distribution of the other enzymes investigated in mink – AP, CK, γ-GT and LD – is much the same as in many other animal species. Their clinical significance in serum is therefore the same.

Sammanfattning

Aktiviteten och den relativa fördelningen av åita kliniskt viktiga enzymer mättes i nio olika organ hos tio friska minkar. Av de undersökta enzymerna hade OCT, ASAT och ALAT högre absolut aktivitet än hos andra djurarter. Det förmodas vara ett tecken på en adaptation till en hög proteinhalt i fodret. OCT är leverspecifik; även ALAT är relativt leverspecifik. Den höga halten av SDH i njurarna innebär att detta enzym inte i samma grad är leverspecifikt. Organdistributionen av övriga enzymer kontrollerade i denna undersökning – AP, CK, γ-GT och LD – är ungefär densamma som hos många andra djurarter. Variation i serumvärdena av dessa enzymer har alltså ungefär samma kliniska betydelse hos mink som hos dessa.

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Juokslahti, T., Lindberg, P. & Työppönen, J. Organ Distribution of Some Clinically Important Enzymes in Mink. Acta Vet Scand 21, 347–353 (1980). https://doi.org/10.1186/BF03546866

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