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Extraglomerular Lesions in Kidneys of Mink with Encephalitozoonosis

Ekstraglomerulœre nyreforandringer hos mink ved encephalitozoonose

Abstract

Extraglomerular renal lesions were studied by light and electron microscopy in 13 farmed mink which showed cataractous eyes associated with spontaneous encephalitozoonosis. The extraglomerular renal lesions consisted of multiple renal cysts, multifocal-to-coalescing interstitial nephritis and vasculitis. Tubular cysts of varying size were present in the corticomedullary junction and medulla. The inflammatory infiltrates were composed mostly of lymphocytes and plasma cells and usually accompanied an interstitial fibrosis. Vasculitis, perivasculitis and sclerotic arteries were frequently seen.

Sammendrag

De ekstraglomerulœre forandringene i nyrene ble studert i lysmikroskopiske og elektronmikroskopiske preparater hos 13 mink. Alle dyra hadde dobbeltsidig katarakt og var spontant infiserte, sannsynligvis på fosterstadiet. Forandringene bestod av multiple cyster, multifokale betennelsesforandringer som delvis konfluerte til større lesjoner, og vaskulitt. De tubuläre cystene var av noe forskjellig størrelse og forekom i medulla og på overgangen mellom medulla og cortex. Betennelsesinfiltratene bestod vesentlig av lymfocytter og plasmaceller og var ledsaget av interstitiell fibrose. Vaskulitt, perivaskulitt og sklerotisering i arteriene forekom ofte.

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Zhou, Zy., Nordstoga, K. & Bjerkås, I. Extraglomerular Lesions in Kidneys of Mink with Encephalitozoonosis. Acta Vet Scand 33, 33–41 (1992). https://doi.org/10.1186/BF03546934

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