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Blood Serum Characteristics of Newborn Pigs: Comparison of Unaffected Pigs with Pigs Belonging to Five Mortality Groups

Blod serum parametre hos nyfødte grise: En sammenligning mellem normale grise og grise fra 5 forskellige mortalitetsgrupper.

Acta Veterinaria Scandinavica volume 32, pages 287–299 (1991)Cite this article

Abstract

The blood serum levels of glucose, hemoglobin, insulin, Cortisol, albumin, alpha-fetoprotein, alpha2-macroglobulin f and s, alpha2-antitrypsin inhibitor and alpha1-protease inhibitor were determined at birth in 5 clinically and morphologically identified mortality groups of pigs. These were compared with the levels observed in unaffected, apparently normal newborn unsuckled pigs. The blood serum profile of the pigs in the stillborn intra partum, weak, splayleg and trauma groups, respectively, as well as that of clinically normal splayleg littermates, differed significantly from that of the unaffected pigs. This was especially true for the levels of hemoglobin and the two macroglobulins. The importance of placental insufficiency causing chronic episodes of hypoxia which ultimately lead to a disturbance in organ development in the etiology of the mortality groups is discussed.

Sammenfatning

Blodserum koncentrationen af glukose, hæmoglobin, insulin, Cortisol, albumin, alpha-fetoprotein, alpha2-makroglobulin f og s, alpha2-antitrypsin inhibitor og alpha1-protease inhibitor blev bestemt ved fødslen i 5 kliniskt og morfologiskt forskellige mortalitetsgrupper, og sammenlignet med resultaterne fra nyfødte, tilsyneladende normale, udiede grise fra samme besætning. Blodserum billedet af grise som døde under fødslen, og af svagfødte grise, svømmere, og grise som blev trampet af soen, og af søskende til svømmere, var signifikant forskelligt fra normalgruppen, især med hensyn til koncentrationen af hæmoglobin og de to makroglobuliner. Resultaterne tyder på at mange af de grise som er syge/svage ved fødslen og/eller som dør under perinatal-perioden gentagne gange har været udsat for iltmangel under fosterperioden. Dette kan bl.a. resultere i nedsat-/dårligt udviklet organfunktion. Nogle af de mulige årsager til iltmangel og nedsat næringstilførsel under fosterperioden diskuteres. Hæmoglobinkoncentration og indeholdet af alpha2-makroglobulin f og s i blodserum er gode markører for nyfødte grises vitalitet.

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Authors and Affiliations

  1. Department of Farm Buildings, Swedish University of Agricultural Sciences, Lund and the Department of Zoophysiology, University of Lund, P. O. Box 945, S-220 09, Lund, Sweden

    L. S. Svendsen, B. R. Weström, J. Svendsen, A.-Ch. Olsson & B. W. Karlsson

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  1. L. S. Svendsen
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  2. B. R. Weström
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  3. J. Svendsen
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  4. A.-Ch. Olsson
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  5. B. W. Karlsson
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Svendsen, L.S., Weström, B.R., Svendsen, J. et al. Blood Serum Characteristics of Newborn Pigs: Comparison of Unaffected Pigs with Pigs Belonging to Five Mortality Groups. Acta Vet Scand 32, 287–299 (1991). https://doi.org/10.1186/BF03546957

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Acta Veterinaria Scandinavica

ISSN: 1751-0147