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Canine Lymphocytic Plasmocytic Enteritis: An Immunopathological Investigation of Intestinal Plasma Cells

Lymfocytær-plasmacytær enteritis: En immunopatologisk undersøgelse af plasmaceller i tarmen

Acta Veterinaria Scandinavica volume 32, pages 221–232 (1991)Cite this article

Abstract

The numbers of IgA-, IgG- and IgM-containing plasma cells in the lamina propria of duodenum, jejunum, ileum, and coecum were quantitated in 3 patients suffering from lymphocytic plasmacytic enteritis and 3 normal control dogs. A great increase was found in all 3 types of plasmacells and at all levels of the intestinal tract. Especially the IgG-containing cells showed a remarkable increase particularly in 2 patients. The possible reasons for these heavy infiltrations of immunologically competent cells are discussed, and chronic antigenic stimulations of food origin is suggested.

Sammendrag

Antallet af IgA, IgG og IgM producerende plasmaceller i lamina propria i duodenum, jejunum, ileum og coecum blev bestemt hos 3 patienter med lymfocytær-plasmacytær enteritis og 3 normale kontrol hunde.

Der fandtes en stor stigning i alle tre typer plasmaceller på alle niveauer af tarmkanalen. De IgG holdige plasmaceller viste en særlig markant stigning specielt hos 2 patienter. Mulige årsager til disse voldsomme infiltrationer af immunologisk kompetente celler diskuteres, og en kronisk fødemiddel antigen stimulation foreslåes.

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Authors and Affiliations

  1. Department of Clinical Studies, Royal Veterinary and Agricultural University, Copenhagen, Bülowsvej 13, DK-1870, Frederiksberg C, Denmark

    Gunvor Vïbe-Petersen

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  1. Gunvor Vïbe-Petersen
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Vïbe-Petersen, G. Canine Lymphocytic Plasmocytic Enteritis: An Immunopathological Investigation of Intestinal Plasma Cells. Acta Vet Scand 32, 221–232 (1991). https://doi.org/10.1186/BF03546984

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Keywords

Acta Veterinaria Scandinavica

ISSN: 1751-0147