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The Influence of Supplements of Selenite, Selenate and Selenium Yeast on the Selenium Status of Dairy Heifers

Effekten av tillförsel av selenit, selenat och selenjäst på kvigors selenstatus

Acta Veterinaria Scandinavica volume 40, pages 23–34 (1999)Cite this article

Abstract

The aim of the study was to define possible differences between selenite, selenate and selenium yeast on various aspects of selenium status in growing cattle. Twenty-four Swedish Red and White dairy heifers were fed no supplementary selenium for 6 months. The basic diet contained 0.026 mg selenium/kg feed dry matter (DM). After the depletion period the animals were divided into 4 groups; group I–III received 2 mg additional selenium daily as sodium selenite, sodium selenate, and a selenium yeast product, respectively. Group IV, the control group, received no additional selenium. The total dietary selenium content for groups I–III during the supplementation period was 0.25 mg/kg DM. After the depletion period the mean concentration of selenium in blood (640 nmol/l) and plasma (299 nmol/l) and the activity of GSH-Px in erythrocytes (610 µkat/l) were marginal, but after 3 months of supplementation they were adequate in all 3 groups. The concentration of selenium in blood and plasma was significantly higher in group III than in groups I and II, but there was no significant difference between groups I and II. The activity of GSH-Px in erythrocytes did not differ between any of the supplemented groups. The animals in the control group had significantly lower concentrations of selenium in blood and plasma and lower activities of GSH-Px in erythrocytes than those in the supplemented groups. The activity of GSH-Px in platelets was also increased by the increased selenium intake. There was no difference in the concentration of triiodothyronine (T3) between any of the groups, but the concentration of thyroxine (T4) was significantly higher in the unsupplemented control group.

Sammandrag

Under en sexmånaders period gavs 24 rekryteringskvigor en icke- selenberikad foderstat innehållande 0,026 mg selen/kg torrsubstans (ts). Djuren delades därefter in i 4 grupper. Grupp I erhöll under 3 månader via fodret ett dagligt tillskott på 2 mg selen i form av natriumselenit. Grupp II gavs samma mängd selen som natriumselenat och grupp III samma mängd organiskt selen i form av ett selenjästpreparat. Grupp IV (kontrollgruppen) erhöll inget selentillskott. Det totala seleninnehållet i de berikade foderstaterna var 0,25 mg/kg ts. När selensupplementeringen påbörjades var seleninnehållet i helblod och plasma 640 resp. 299 nmol/l och GSH-Px aktiviteten i erytrocyterna 610 µkat/l, vilket innebär art djuren hade ett selenstatus som låg nära bristnivån. Vid försökets slut hade samtliga supplementerade grupper ett fullgott selenstatus, medan inga förändringar hade skett i kontrollgruppen. Djuren i grupp III hade vid försökets slut signifikant högre halt av selen i blod och plasma än de i grupp I och II, under det art inga skillnader forelåg beträffande GSH-Px aktiviteten i erytrocyter.

GSH-Px aktiviteten i trombocyter ökade också efter selentillförseln. Det förelåg ingen skillnad mellan några grupper vad avser trijodtyronin (T3) i plasma, däremot hade kontrollgruppens djur en signifikant högre halt av thyroxin (T4) i plasma.

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Authors and Affiliations

  1. Department of Animal Environment and Health, Section of Field Research, Faculty of Veterinary Medicine, Swedish University of Agrucultural Sciences, P.O. Box 234, S-532 23, Skara, Sweden

    K. Ortman & R. Andersson

  2. Department of Clinical Chemistry, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, Uppsala, Sweden

    H. Holst

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  1. K. Ortman
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  2. R. Andersson
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  3. H. Holst
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Correspondence to K. Ortman.

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Ortman, K., Andersson, R. & Holst, H. The Influence of Supplements of Selenite, Selenate and Selenium Yeast on the Selenium Status of Dairy Heifers. Acta Vet Scand 40, 23–34 (1999). https://doi.org/10.1186/BF03547038

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Acta Veterinaria Scandinavica

ISSN: 1751-0147