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The Pathogenesis of Hydrallantois Bovis II. Electrical Potential and Chemical Gradients Between the Allantoic Fluid and the Maternal Blood in Hydrallantois and Normal Pregnancy

Die Pathogenese der Hydrallantois bovis. II Elektrische Potentiale und chemische Gradienten zwischen Allantoisflüssigkeit und Mutterblut beim Vorliegen der Hydrallantois im Gegensatz zur normalen Trächtigkeit

Patogenesen ved hydrallantois bovis. II. Elektriske potentialer og kemiske gradienter mellem allantoisvæsken og det maternelle blod ved hydrallantois og normal drægtighed

Summary

Compared to normal pregnancy an evident reduction of the electrical potentials and electrochemical gradients was found in cases of hydrallantois without primary foetal deformity. The permeability of chorio-allantois in vitro was distinctly increased in some extreme cases of the disease.

It is suggested that the pathogenesis may be a primary decrease in active transport of ions across the chorion, followed by a mechanical destruction of the micro-structure of the chorio-allantoic membranes.

Zusammenfassung

Verglichen mit der normalen Trächtigkeit waren die elektrischen Potentiale und elektrochemischen Gradienten beim Zustand der Hydrallantois ohne primäre Missbildungen der Frucht auffallend niedriger. Die Permeabilität der Allantochorion war bei einigen extremen Fällen der Krankheit in Vitro deutlich erhöht.

Die Ergebnisse lassen vermuten, dass die Pathogenese mit einem primär verringerten aktiven Ionentransport durch das Chorion gefolgt von einer mechanischen Zerstörung der Mikrostruktur des Allantochorions in Verbindung steht.

Sammendrag

Sammenlignet med normal drægtighed fandtes de elektriske potentialer og elektrokemiske gradienter nedsat i tilfælde af hydrallantois uden primær misdannelse af fosteret. Allantochorions permeabilitet in vitro var tydeligt forøget i nogle extreme tilfælde af sygdommen.

Resultaterne lader formode, at patogenesen kan være forbundet med en primært nedsat aktiv iontransport gennem chorion efterfulgt af mekanisk destruktion af allantochorions mikrostruktur.

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Correspondence to J. M. Skydsgaard.

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This investigation has been supported by Statens almindelige Videnskabsfond and Novofonden.

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Skydsgaard, J. The Pathogenesis of Hydrallantois Bovis II. Electrical Potential and Chemical Gradients Between the Allantoic Fluid and the Maternal Blood in Hydrallantois and Normal Pregnancy. Acta Vet Scand 6, 208–216 (1965). https://doi.org/10.1186/BF03547077

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