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The Intestinal Flora in Pigs with Parakeratosis V. Clostridium Perfringens Alpha Antitoxin Levels in Blood Serum

Die Darmflora bei Schweinen mit Parakeratose

Tarmfloran hos grisar med parakeratos

Summary

Pigs which develop parakeratosis acquire increased alpha antitoxin values in blood serum. The determination of the occurrence of alpha antitoxin in serum has confirmed earlier results concerning the presence of antibodies against intestinal Clostridium perfringens and has, furthermore, — from a methodological point of view — given more clear cut results than the agglutination and precipitation tests. The observation that even at the beginning of the experiment all the pigs showed alpha antitoxin in serum is discussed.

Zusammenfassung

V. Bestimmung der Alpha-Antitoxin-Mengen in Blutserum.

Bei Schweinen die an parakeratose erkranken sind die AlphaAntitoxinmengen in Blutserum erhöht. Frühere Untersuchungen über das Vorkommen von Antikörpern gegen Clostridium perfringens sind dadurch bestätigt. Das Verfahren, die Alpha-Antitoxinmenge in Blutserum festzustellen, scheint distinktere Resultate als die Agglutinationsund Präzipitationsmethoden zu geben. Schon im Anfang des Versuches vorkommende Alpha-Antitoxin ist diskutiert.

Sammanfattning

V. Förekomst av alfa antitoxin i serum.

Hos grisar, som insjuknat i parakeratos, har påvisats förhöjda alfa antitoxin värden i serum. Tidigare gjorda iakttagelser beträffande förekomsten av cirkulerande antikroppar mot Clostridium perfringens vid denna sjukdom har därigenom bekräftats. Undersökningen av alfa antitoxin i serum har skett med en metod, som givit klarare resultat än agglutinations- och precipitationsundersökningarna. Det har kunnat iakttagas, att grisarna redan vid försökets början visade positiva alfa antitoxin värden. Detta förhållande diskuteras.

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Correspondence to Ingmar Månsson.

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Månsson, I. The Intestinal Flora in Pigs with Parakeratosis V. Clostridium Perfringens Alpha Antitoxin Levels in Blood Serum. Acta Vet Scand 6, 261–267 (1965). https://doi.org/10.1186/BF03547083

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