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Excretion of Selenium in the Milk of Sheep

Die Ausscheidung von Selenium in der Milch von Schafen

Utsöndring av selen i mjölken hos får

Summary

The excretion of selenium in milk was investigated in twelve ewes. Four of these were injected 12–29 days before, and four immediately after delivery, with Se75-sodium selenite. One month after delivery two ewes were injected with Se75-selenomethionine, and two with Se75-sodium selenite. The Se75-concentration was measured in the milk and its various fractions as well as in the plasma, whole blood and organs of three lambs.

The excretion of Se75 into the milk was markedly higher when Se75-selenomethionine was administered than when Se75-sodium selenite was given. The amount of Se75 in the various milk fractions was, to a great extent, proportional to the amount of protein in the fractions; this applied to the administration of organic as well as inorganic selenium. The highest Se75-concentration in the milk was obtained already within 24 hours after injection. Selenium administered before delivery gave the highest concentration in samples taken less than six hours after delivery. The lambs which received Se75 via the milk had a higher content of Se75 than those who received it during the fetal period.

Zusammenfassung

Die Ausscheidung von Selen mit der Milch wurde bei 12 Mutterschafen untersucht. Vier von diesen wurde Se75-Natriumselenit 12–29 Tage vor dem Partus und vier Mutterschafen unmittelbar nach demselben injiziert. Einen Monat nach dem Partus erhielten zwei Mutterschafe Se75-Selenmethionin und zwei Mutterschafe Se75-Natriumselenit injiziert. Der Gehalt an Se75 wurde ausser in Vollmilch und in deren verschiedenen Fraktionen, im Vollblut, Plasma und in Organen bestimmt.

Die Ausscheidung von Se75 mit der Milch war nach der Zufuhr von Se75-Selenmethionin markant höher als nach der Verabreichung von Se75-Selenit. Der Gehalt verschiedener Fraktionen an Se75 verhielt sich zum grossen Teil proportional zum Eiweissgehalt der entsprechenden Fraktion, gleichgültig ob dasselbe in organischer oder anorganischer Form gegeben wurde. Die höchste Se75-Konzentration in der Milch wurde schon innerhalb von 24 Stunden nach der Injektion nachgewiesen. Wurde dieselbe vor dem Partus ausgeführt, so erreichte die Konzentration ihr Maximum in den Proben, welche früher als sechs Stunden nach dem Partus entnommen worden waren. Die Übertragung von Se75 auf das Lamm in der entsprechenden Zeit war auf dem Wege der Milch grösser als auf dem Wege der Plazenta.

Sammanfattning

Utsöndringen av seien med mjölken undersöktes hos 12 tackor. Fyra av dessa injicerades 12–29 dygn före och fyra strax efter förlossningen med Se75-natriumselenit. En månad efter förlossningen injicerades två tackor med Se75-selenmetionin och två med Se75-natriumselenit. Halten Se75 mattes utom i helmjölk och dess olika fraktioner i helblod, plasma och organ.

Utsöndringen av Se75 i mjölken var markant högre vid tillförsel av Se75-selenmetionin an vid tillförsel av Se75-selenit. Halten Se75 i olika fraktioner var till stor del proportioneli till äggvitehalten i respektive fraktion oavsett om det tillfördes i organisk eller oorganisk form. Högsta Se75-koncentrationen i mjölken påvisades redan inom 24 timmar efter injektionen. Om denna gjordes före förlossningen var koncentrationen högst i proven som togs mindre an sex timmar efter partus. överföringen av Se75 till lammen var större via mjölken än via placenta under motsvarande tid.

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Correspondence to S. O. Jacobsson.

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This investigation was supported by a grant from the Swedish Agricultural Research Council.

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Jacobsson, S., Oksanen, H. & Hansson, E. Excretion of Selenium in the Milk of Sheep. Acta Vet Scand 6, 299–312 (1965). https://doi.org/10.1186/BF03547087

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