Skip to main content

Haemolytig Escherichia Coli Serotypes Isolated From Pigs, Cattle, Dogs, and Cats

Hämolytische Escherichia Coli Serotypen isoliert von Schweinen, Rindern, Hunden und Katzen

Serologisk undersökning au hämolyserande Escherichia coli, som isolerais från svin, not, hund och katt

Summary

Of 272 haemolytic strains of E. coli studied, 209 or 76.8 per cent belonged to 5 O-groups — 14 to O 2, 24 to O 6, 79 to O 138, 6 to O 139, and 86 to O 141. The strains were isolated from pigs, cattle, dogs, and cats. The distribution of the various serotypes among isolates from the different species is shown in Tables 3 a and 3 b.

The serotypes O 141 :K 85(B) : (H 1) and 0 138: K 81(B) : (H 14) were the most common types recovered from pigs, usually in association with acute enteritis — often haemorrhagic — and septicaemia in animals 4 to 10 weeks of age. Serotype O 141 :K 85(B) : (H 1) was also isolated from dogs and cats. Strains belonging to O-groups 2 and 6 were recovered from pigs, cattle, and dogs, usually in association with local inflammatory lesions (cystitis, pneumonia, enteritis etc.).

Serotype O 138: K 81(B) : (H 14) was also isolated from cattle. Serotype O 139 :K 82(B) :H 1 was isolated from pigs and cattle. The haemolytic properties of the strains are discussed. With one exception no examples of “oedema disease” were seen.

Zusammenfassung

209 von 272 hämolytischen E. Coli Stämmen (76,8%) gehörten zu 5 verschiedenen O-Gruppen, nämlich O-Gruppe 2 14St. O-Gruppe 6 24St. O-Gruppe 138 79St. O-Gruppe 139 6 St. und O-Gruppe 141 86St.

Die Stämme wurden von Schweinen, Rindern, Hunden und Katzen isoliert. Die Verteilung der verschiedenen Serotypen innerhalb der verschiedenen Tierarten geht aus den Tabellen 3 a und 3 b hervor.

Die Serotypen O 141 :K 85(B) : (H 1) und O 138: K 81(B) : (H 14) kamen gewöhnlich bei Schweinen vor und wurden in der Regel im Zusammenhang mit akuten Enteriten isoliert — meistens hämorrhagische — mit Sepsis bei Schweinen im Alter von 4–10 Wochen. Serotyp O 141 :K 85(B) : (H 1) kam auch bei Hunden und Katzen vor. Stämme die zur O-Gruppe 2 und 6 gehörten kamen bei Schweinen, Rindern und Hunden vor, meistens im Zusammenhang mit lokalen Infektionen (Cystiten, Pneumonien, Enteriten etc.). O 138:K 81(B) :(H 14) wurde auch von Rindern isoliert. O 139 :K 82(B) : (H 1) wurde von Schweinen und Rindern isoliert. Die hämolysierenden Fähigkeiten der Stämme wird diskutiert. Die Oedem-Krankheit ist mit einer Ausnahme nicht beobachtet worden.

Sammanfattning

209 av 272 häm. E. coli stammar (76,8 %) tillhörde 5 O-grupper, nämligen O-grupp 2 14 st, O-grupp 6 24 st, O-grupp 138 79 st, O-grupp 136 6 st och O-grupp 141 86 st. Stammarna var isolerade från svin, not, hundar och katter. De olika serotypernas fördelning inom de olika djurslagen framgår av Tabeli 3 a och 3 b.

Serotyperna O 141.-K 85(B): (H1) och O 138:K 81(B) : (H 14) var vanligast förekommande hos grisar och hade som regel isolerats i samband med akuta enteriter — ofta hämorrhagiska — med sepsis hos grisar i åldern 4–10 veckor. Serotypen O 141 :K 85(B) : (H 1) forekom också hos hund och katt. O 2 och O 6 stammar tprekom hos svin, not, hund of tast i samband med lokala infektioner (cystit, pneumoni, enterit etc.). O 138:K 81(B) : (H 14) isolerades även från not. 0 139: K 82(B) :H 1 isolerades från svin och not. Hämolysförmagan hos stammarna diskuteras. Oedema disease har med ett undantag ej iakttagits.

References

  1. Campbell, S. G.: Studies on strains of haemolytic Escherichia coli isolated from normal swine after weaning. Vet. Rec. 1959, 71, 900.

    Google Scholar 

  2. Davis, J. W., Allen, R. G. and Suribert, R. M.: Studies on hemolytic Escherichia coli associated with edema disease of swine. I. Separation and properties of a toxin of hemolytic Escherichia coli. Amer. J. vet. Res. 1961, 22, 736.

    CAS  PubMed  Google Scholar 

  3. Edwards, P. R. and Ewing, W. H.: Identification of Enterobacteriaceae. Minneapolis, 1955.

  4. Erskine, R. G., Sojka, W. J. and Lloyd, M. K.: The experimental reproduction of a syndrome indistinguishable from oedema disease. Vet. Rec. 1957, 69, 301.

    Google Scholar 

  5. Ewertsen, H. W.: Dyreexperimentelle Undersøgelser over Colibacillernes Pathogenitet og Effekten af Goliserum. Copenhagen, 1946.

  6. Ewing, W. H., Tatum, H. W. and Davis, B. R.: Escherichia coli serotypes associated with edema disease of swine. Cornell Vet. 1958, 48, 201.

    CAS  PubMed  Google Scholar 

  7. Fey, H.: Serologische, biochemische und biologische Untersuchungen an Stämmen aus boviner Colimastitis. Zürich, 1954.

  8. Gitter, M.: Haemolytic Bact. coli in the “bowel oedema” syndrome. Part. I — An attempted investigation into the pathogenicity of the organism for experimental animals. Brit. vet. J. 1957, 113, 168.

    Google Scholar 

  9. Gitter, M. and Lloyd, M. K.: Haemolytic Bact. coli in the “bowel oedema” syndrome. Part. II — Transmission and protection experiments. Brit. vet. J. 1957, 113, 212.

    Google Scholar 

  10. Gregory, D. W.: Role of beta hemolytic coliform organisms in edema disease of swine. Vet. Med. 1955, 50, 609.

    Google Scholar 

  11. Gregory, D. W.: Edema disease /E coli toxemia/ of swine. Vet. Med. 1958, 53, 77.

    Google Scholar 

  12. Gregory, D. W.: Experimental edema disease /hemolytic Escherichia coli toxemia/ in pigs and in mice. Amer. J. vet. Res. 1960, 21, 88.

    CAS  Google Scholar 

  13. Hess, E. und Suter, P.: Die Ödemkrankheit des Schweines. Schweiz. Arch. Tierheilk. 1958, 100, 653.

    Google Scholar 

  14. Ito, A.: Studies on hemolytic Escherichia coli strains isolated from edema disease of swine in Japan. Jap. J. vet. Res. 1960, 8, 215.

    Google Scholar 

  15. Kauffmann, F.: Enterobacteriaceae. Copenhagen. 1954.

  16. Lannek, N.: 1961. Personal communication.

  17. Månsson, L: Septic enteritis caused by haemolytic coliform bacteria. Preliminary report. XVI:th International Vet. Congr. Madrid, 1959, p. 529.

  18. Månsson, I.: Haemolytic E. coli in diseased and healthy animals on a particular premises. Acta vet. scand. 1962. In press.

  19. Ørskou, F.: 1961. Personal communication.

  20. Quinchon, A., Henry, M. and Mme Henry, G.: Le syndrome entérotoxique colibacillaire du porcelet. Réc. Méd. Vét. 1958, 134, 437.

    Google Scholar 

  21. Rees, T. A.: Studies on Escherichia coli of animal origin. 3. E. coli serotypes from pigs. J. comp. Path. 1959, 69, 334.

    CAS  Google Scholar 

  22. Richards, W. P. C. and Frazer, C. M.: Coliform enteritis of weaned pigs. A description of the disease and its association with hemolytic Escherichia coli. Cornell Vet. 1961, 51, 245.

    CAS  PubMed  Google Scholar 

  23. Roberts, H. E. and Vallely, T. F.: An investigation into the relationship of haemolytic Escherichia coli to disease in pigs. Vet. Rec. 1959, 71, 846.

    Google Scholar 

  24. Saunders, C. V., Stevens, A. J., Spence, J. B. and Sojka, W. J.: Escherichia coil infection in piglets. Res. vet. Sci. 1960, 1, 28.

    Google Scholar 

  25. Schofield, F. W. and Davis, D.: Oedema disease /enterotoxemia/ in swine. II. Experiments conducted in a susceptible herd. Canad. J. comp. Med. 1955, 19, 242.

    CAS  Google Scholar 

  26. Sjöstedt, S.: Pathogenicity of certain serological types of B. coli. Lund, 1946.

  27. Sojka, W. J., Erskine, R. G. and Lloyd, M. K.: Hemolytic Escherichia coli and “oedema disease” of pigs. Vet. Rec. 1957, 69, 293.

    Google Scholar 

  28. Sojka, W. J., Lloyd, W. J. and Sweeny, E. J.: Escherichia coli serotypes associated with certain pig diseases. Res. vet. Sci. 1960, 1, 17.

    Google Scholar 

  29. Terpstra, J. I.: Haemolytische colibakterien als oorzaak van ziekte bij het varken. Tijdschr. Diergenesk. 1958, 83, 1078.

    Google Scholar 

  30. Timoney, J. F.: Experimental production of oedema disease of swine. Vet. Rec. 1949, 61, 710.

    Google Scholar 

  31. Timoney, J. F.: Oedema disease in swine. Ibid. 1950, 62, 748.

    CAS  Google Scholar 

  32. Timoney, J. F.: Oedema disease of swine. Ibid. 1956, 68, 849.

    Google Scholar 

  33. Timoney, J. F.: Oedema disease in swine. Ibid. 1957, 69, 1160.

    Google Scholar 

  34. Vahlne, G.: Serological typing of the Colon Bacteria. Acta path, microbiol. scand. Suppl. LXII, 1945.

  35. Wramby, G.: Investigations into the antigenic structure of Bact. coli isolated from calves. Acta path, et microbiol. scand. Suppl. LXXVI, 1948.

Download references

Authors

Additional information

This work has been supported by a grant from Statens medicinska forskningsråd.

It has long been recognised that Escherichia coli, although part of the normal intestinal flora, can also cause infections in human beings and animals. For many years there were no means of accurately typing the various strains isolated. This difficulty naturally hindered study of the significance of these organisms for the infectious diseases with which they were associated. Extensive investigations, particularly by Kauffmann and his associates, have now clarified many of the serological properties of E. coli. Strains isolated from diseased and normal organs can now be identified and many conclusions of practical value reached.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Månsson, I. Haemolytig Escherichia Coli Serotypes Isolated From Pigs, Cattle, Dogs, and Cats. Acta Vet Scand 3, 65–78 (1962). https://doi.org/10.1186/BF03547130

Download citation