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Distribution of Se75-Tagged Sodium Selenite in Pigs With Nutritional Muscular Dystrophy

Verteilung von Se75-gekennzeichnetem Natriumselenit bei Ferkeln mit diätbedingter Muskeldystrophie

Fördelning av Se75-märkt natriumselenit hos grisar med utfodringsbetingad muskeldystrofi

Summary

Sodium-selenite-Se75 was given as an intramuscular injection to pigs fed on a dystrophogenic diet. An examination for radioactivity of organs at slaughter 1 to 22 days after administration showed that pigs affected with muscular (and liver) dystrophy did not concentrate more selenium in muscles and organs than do healthy animals.

Zusammenfassung

Den Ferkeln gehalten bei einer Muskeldystrophieerzeugender Diät, wurde intramuskulär eine Injektion Natriumselenit-Se75 gegeben. Die Feststellung des Radioselen-Gehaltes in Organen der geschlachteten Ferkeln mach 1 bis 22 Tage ergab, dass die Ferkeln mit einer Muskeldystrophie (und gleichzeitiger Leberdystrophie) nicht mehr Selen in der Muskulatur und den Organen konzentrierten als gesunde Tiere.

Sammanfattning

Natriumselenit-Se75 gavs som en intramuskulär injektion till grisar, som stod på en muskeldystrofiframkallande diet. En undersökning av radioselen-halten i grisarnas organ vid slakt 1–22 dagar senare visade att grisar med muskeldystrofi (och leverdystrofi) inte koncentrerade mera selen i muskulatur och organ än friska djur.

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GOT = Glutamic-oxaloacetic transaminase. OCT = ornithine carbamyl transferase

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Ekman, L., Orstadius, K. & Åberg, B. Distribution of Se75-Tagged Sodium Selenite in Pigs With Nutritional Muscular Dystrophy. Acta Vet Scand 4, 92–96 (1963). https://doi.org/10.1186/BF03547175

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  • DOI: https://doi.org/10.1186/BF03547175