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Distribution of Se75-Tagged Sodium Selenite in Pigs With Nutritional Muscular Dystrophy

Verteilung von Se75-gekennzeichnetem Natriumselenit bei Ferkeln mit diätbedingter Muskeldystrophie

Fördelning av Se75-märkt natriumselenit hos grisar med utfodringsbetingad muskeldystrofi


Sodium-selenite-Se75 was given as an intramuscular injection to pigs fed on a dystrophogenic diet. An examination for radioactivity of organs at slaughter 1 to 22 days after administration showed that pigs affected with muscular (and liver) dystrophy did not concentrate more selenium in muscles and organs than do healthy animals.


Den Ferkeln gehalten bei einer Muskeldystrophieerzeugender Diät, wurde intramuskulär eine Injektion Natriumselenit-Se75 gegeben. Die Feststellung des Radioselen-Gehaltes in Organen der geschlachteten Ferkeln mach 1 bis 22 Tage ergab, dass die Ferkeln mit einer Muskeldystrophie (und gleichzeitiger Leberdystrophie) nicht mehr Selen in der Muskulatur und den Organen konzentrierten als gesunde Tiere.


Natriumselenit-Se75 gavs som en intramuskulär injektion till grisar, som stod på en muskeldystrofiframkallande diet. En undersökning av radioselen-halten i grisarnas organ vid slakt 1–22 dagar senare visade att grisar med muskeldystrofi (och leverdystrofi) inte koncentrerade mera selen i muskulatur och organ än friska djur.


  1. Ekman, L.: Distribution and excretion off radio-cesium in goats, pigs and hens. Acta vet. scand. 1961, 2, suppl. 4.

  2. Grant, C. A., Thafvelin, B. and Christell, R.: Retention of Selenium by Pig Tissues. Acta pharm, toxicol. scand. 1961, 18, 285–297.

    CAS  Article  Google Scholar 

  3. Lindberg, P. and Orstadius K.: Production of muscular dystrophy in pigs by feeding cottonseed oil. Acta vet. scand. 1961, 2, 226–235.

    Google Scholar 

  4. Magnusson, G. and Orstadius, K.: Relation between the plasma level of glutamic-oxaloacetic transaminase and the morphological status of skeletal muscle in pigs. In press.

  5. Orstadius, K., Nordström, G. and Lannek, N.: Gombined therapy with vitamin E and selenite in experimental nutritional muscular dystrophy of pigs. In press.

  6. Orstadius, K., Wretlind, B., Lindberg, P., Nordström, G. and Lannek, N.: Plasma-transaminase and transferase activities in pigs affected with muscular and liver dystrophy. Zbl. Vet. Med. 1959, 6, 971 –980.

  7. Orstadius, K. and Åberg, B.: Distribution of Se75-tagged sodium selenite in pigs. Acta vet. scand. 1961, 2, 60–67.

    CAS  Google Scholar 

  8. Reichard, H.: Determination of ornithine carbamyl transferase with microdiffusion technique. Scand. J. clin. Lab. Invest. 1957, 9, 311–314.

    CAS  Article  Google Scholar 

  9. Reitman, S. and Frankel, S.: A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases. Amer. J. clin. Path. 1957, 28, 56–63.

    CAS  Article  Google Scholar 

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GOT = Glutamic-oxaloacetic transaminase. OCT = ornithine carbamyl transferase

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Ekman, L., Orstadius, K. & Åberg, B. Distribution of Se75-Tagged Sodium Selenite in Pigs With Nutritional Muscular Dystrophy. Acta Vet Scand 4, 92–96 (1963).

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