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Haptoglobin Polymorphism in Pigs

Haptoglobinpolymorphie beim Schwein

Haptoglobinpolymorfi hos svin

Summary

In a starch gel electrophoretic study of sera from pigs of the Danish Landrace protein polymorphism involving four haptoglobins designated Hp 0, Hp 1, Hp 2 and Hp 3 was observed. Each component either occurred singly or together with only one of the three other components.

Each individual pig investigated exhibited one of ten serum phenotypes with respect to Hp 0, Hp 1, Hp 2 and Hp 3.

Studies within families supported the hypothesis that the polymorphism was genetically controlled and determined by four alleles, Hp0, Hp1, Hp2 and Hp3, with codominance. The phenotypes and the corresponding genotypes are shown in figure 1.

Zusammenfassung

Das stärkeelektrophoretische Studium von Seren von Schweinen der dänischen Landrasse ergab Proteinpolymorphie in bezug auf 4 Haptoglobinkomponenten: Hp 0, Hp 1, Hp 2 und Hp 3. Jede Komponente kam entweder allein oder zusammen mit nur einer der anderen drei Komponenten vor.

Auf Grund des Vorkommens der 4 Haptoglobine in Seren wiesen sämtliche untersuchten Tiere einen von 10 Serumphänotypen auf.

Familienuntersuchungen stützten die Hypothese, dass die Polymorphie genetisch bedingt war und unter der Kontrolle von 4 Allelen, Hp0, Hp1, Hp2 und Hp3, ohne Dominanz, stand. Die zehn Phänotypen und die entsprechenden Genotypen sind in Figur 1 dargestellt.

Resumé

Ved et stivelsegelelektroforetisk studium af sera fra svin af Dansk Landrace blev der påvist proteinpolymorfi med hensyn til 4 haptoglobinkomponenter: Hp 0, Hp 1, Hp 2 og Hp 3. Hver komponent forekom enten alene eller sammen med kun een af de andre tre komponenter.

På grundlag af forekomsten i sera af de 4 haptoglobiner udviste samtlige undersøgte dyr een af 10 serumfænotyper.

Familieundersøgelser støttede hypotesen om, at polymorfien var genetisk bestemt og under kontrol af 4 alleler, Hp0, Hp1, Hp2 og Hp3, uden dominans. De ti fænotyper og de tilsvarende genotyper er vist på fig. 1.

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Hesselholt, M. Haptoglobin Polymorphism in Pigs. Acta Vet Scand 4, 238–246 (1963). https://doi.org/10.1186/BF03547186

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  • DOI: https://doi.org/10.1186/BF03547186