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Selective Adherence of Erysipelothrix Rhusiopathiae to Heart Valves of Swine Investigated in an in Vitro Test
Selektiv adhesjon av Erysipelothrix rhusiopathiae til hjerteklaffer fra gris belyst i et in vitro-forsøk
Acta Veterinaria Scandinavica volume 22, pages 39–45 (1981)
Abstract
An in vitro test for the adherence of microorganisms to epithelial surfaces was performed in an attempt to illustrate the initial steps in the establishment of infectious endocarditis. Preparations of fresh heart valves of swine were incubated in suspensions of Erysipelothrix rhusiopathiae. There was a significant difference (P < 0.01) in the degree of adherence between the 5 strains of E. rhusiopathiae investigated. The highest degree of adherence was found in an isolate from an endocardial vegetation and in a strain labelled type A1, both originating from swine. Scanning electron microscopy showed the microorganisms distributed on the endocardial surface and in large numbers at the base of the chordae tendinae.
Sammendrag
Det er utført et in vitro forsøk for adhesjon av Erysipelothrix rhusiopathiae til overflaten av hjerteklaffer for å illustrere det innledende trinn i utviklingen av infeksiøs endokarditt. Ferskt materiale av hjerteklaffer fra gris ble inkubert i oppslemminger av bakterier. Kimtellinger viste en signifikant forskjell (P < 0,01) i adhesjon mellom 5 E. rhusiopathiae-stammer av forskjellig opprinnelse. Størst adhesjon viste en stamme isolert fra en endokardial påleiring og en type A1-stamme, begge isolert fra gris. I scanning elektron mikroskopi sås mikroorganismene spredt over den endokardiale overflate og i størst antall ved basis av chordae tendinae.
References
Burrows, M. R., R. Sellwood & R. A. Gibbons: Haemagglutinating and adhesive properties associated with the K99 antigen of bovine strains of Escherichia coli. J. gen. Microbiol. 1976, 96, 269–275.
Ellen, R. P. & R. J. Gibbons: M protein-associated adherence of Streptococcus pyogenes to epithelial surfaces: prerequisite for virulence. Infect. Immun. 1972, 5, 826–830.
Frost, A. J., D. D. Wanasinghe & J. B. Woodcock: Some factors affecting selective adherence of microorganisms in the bovine mammary gland. Infect. Immun. 1977, 15, 245–253.
Hoeprich, P. D.: Infective endocarditis. In Hoeprich, P. D., ed. Infectious Diseases. 2nd Ed. Harper & Row, Hagerstown, Maryland, New York, San Francisco, London 1979, p. 999–1011.
Jones, G. W. & J. M. Rutter: Role of K88 antigen in the pathogenesis of neonatal diarrhea caused by Escherichia coli in piglets. Infect. Immun. 1972, 6, 918–927.
Jubb, K. V. F. & P. C. Kennedy: Pathology of Domestic Animals. 2nd Ed. Academic Press, New York and London 1970, p. 111–114.
Karnovsky, M. J.: A formaldehyde-glutaraldehyde fixative of high osmolality for the use in electron microscopy. J. Cell. Biol. 1965, 27, 137A–138A.
Kucsera, G.: Proposal for standardization of the designations used for serotypes of Erysipelothrix rhusiopathiae. Int. J. system. Bact. 1973, 23, 184–188.
Nørrung, V.: Studies on Erysipelothrix insidiosa, s. rhusiopathiae. 1. Morphological, cultural features, biochemical reactions and virulence. Acta vet. scand. 1970 a, 11, 517–585.
Nørrung, V.: Studies on Erysipelothrix insidiosa, s. rhusiopathiae. 2. Serological study. Acta vet. scand. 1970 b, 11, 586–593.
Wood, R. L. & R. D. Shuman: Swine erysipelas. In Dunne, H. W. & A. D. Leman, eds. Diseases of Swine, 4th Ed. Iowa State University Press, Ames, Iowa, U.S.A. 1975, p. 565–604.
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Bratberg, A.M. Selective Adherence of Erysipelothrix Rhusiopathiae to Heart Valves of Swine Investigated in an in Vitro Test. Acta Vet Scand 22, 39–45 (1981). https://doi.org/10.1186/BF03547204
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DOI: https://doi.org/10.1186/BF03547204