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Immunological Cross Reactions of Antigens of Erysipelothrix Rhusiopathiae and Heart Tissue From Swine

Immunologiske kryssreaksjoner mellom antigener fra Erysipelothrix rhusiopathiae og hjertevev fra gris

Abstract

Antisera against 4 strains of E. rhusiopathiae and against heart tissues from swine were raised in rabbits and used in gel double diffusion precipitation tests against 10 strains of E. rhusiopathiae of various origins and against heart tissues. Precipitation lines showing cross reactions were found in tests with one bacterial antiserum and with both tissue antisera tested. This indicates a similarity between the antigenic determinants of heart muscle and valves from swine and certain strains of E. rhusiopathiae. The possible relationship between the results and the virulence of the microorganisms is discussed.

Sammendrag

Antisera mot 4 Erysipelothrix rhusiopathiae-stammer og mot hjertevev fra gris ble framstilt på kanin og brukt i agargel dobbeldiffusjonsprøver mot 10 E. rhusiopathiae-stammer av forskj ellig opprinnelse og mot hjertevev. Kryssreaksjoner ble påvist i prøver med et bakterieantiserum og med begge vevsantisera som ble undersøkt. Dette tyder på likhet i antigene determinanter fra hjertemuskulatur og hjerteklaffer og visse stammer av E. rhusiopathiae. Mulighetene for å korrelere resultatene til forskjellige egenskaper av betydning for rødsykebakterienes virulens er kort diskutert.

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Bratberg, A.M. Immunological Cross Reactions of Antigens of Erysipelothrix Rhusiopathiae and Heart Tissue From Swine. Acta Vet Scand 22, 46–54 (1981). https://doi.org/10.1186/BF03547205

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