Skip to main content
  • Published:

Plasma Prolactin in the Sow with Emphasis on Variation in Resumption of Ovarian Activity after Weaning

Plasma prolaktin hos purke spesielt i relasjon til ovarialaktiviteten etter avvenning

Abstract

Plasma prolactin in the sow was studied during pregnancy, lactation and during the post weaning period. The ovarian activity was monitored hy progesterone determinations. In the pregnant sows (2 sows) there was a distinct increase in prolactin values ahout a week before parturition, amounting to maximum levels around parturition. A moderate decrease in prolactin values during the lactation period (3 sows) was observed. After weaning the prolactin values dropped immediately to basal levels. Of the 91 sows studied in the post weaning period 72 sows resumed cyclic ovarian function within normal time (10 days) after weaning while 19 sows had delayed resumption of ovarian activity. The prolactin patterns in sows with prolonged periods of ovarian inactivity were similar to those seen in normal sows. None of our results indicate that post weaning anoestrus is caused by prolonged hyperprolactinaemia after weaning.

Sammendrag

Plasma prolaktin hos purke ble undersøkt under drektighet, laktasjon og i perioden etter avvenning. Purkenes ovarialaktivitet ble undersøkt ved hjelp av progesteronmålinger. Hos de drektige purkene (2 purker) var det en klar stigning i prolaktinnivåene cirka en uke før grising og de høyeste verdiene ble funnet i tiden like rundt partus. I løpet av laktasjonen (3 purker) ble det registrert et moderat fall i prolaktin verdiene. Etter avvenning gikk konsentrasjonene av prolaktin i plasma raskt ned til basalnivået. Av de 91 purkene som ble undersøkt i perioden etter avvenning, ovulerte 72 purker innen 10 dager etter avvenning, mens 19 purker hadde forsinket igangsetting av ovarialfunksjonen. Purkene med forsinket igangsetting av syklisk ovarialfunksjon etter avvenning hadde samme prolaktinmønster som purker som gjenopptok ovarialfunksjonen etter normal tid. Resultatene tyder ikke på at anøstrus hos purke etter avvenning skyldes hyperprolaktinemi.

References

  • Aherne, F. X., R. J. Christopherson, J. R. Thompson & R. T. Hardin: Factors affecting the onset of puberty, post-weaning estrus and blood hormone levels of Lacombe gilts. Canad. J. Anim. Sci. 1976, 56, 681–692.

    Article  CAS  Google Scholar 

  • Baird, D. T.: Endocrinology of female infertility. Brit. med. Bull. 1979, 35, 193–198.

    Article  CAS  Google Scholar 

  • Benjaminsen, E. & K. Karlberg: Blodprøvetaking av gris. (Blood sampling in the pig). Norsk Vet.-Tidsskr. 1979, 91, 15–17.

    Google Scholar 

  • Benjaminsen, E. & K. Karlberg: Post weaning oestrus and luteal function in primiparous and pluriparous sows. Res. Vet. Sci. 1981, in press.

  • Beuers, M. M., A. H. Willemse & Th. A. M. Kruip: Plasma prolactin levels in the sow during lactation and the postweaning period as measured by radioimmunoassay. Biol. Reprod. 1978, 19, 628–634.

    Article  Google Scholar 

  • Brown, J. B., R. D. Bulbrook & F. C. Greenwood: An evaluation of a chemical method for the estimation of estriol, oestrone and oestradiol-17β in human urine. J. Endocr. 1957, 16, 41–48.

    Article  CAS  Google Scholar 

  • Edquist, L. E., S. Einarsson & I. Settergren: Ovarian activity and peripheral plasma levels of oestrogens and progesterone in the lactating sow. Theriogenology 1974, 1, 43–49.

    Article  Google Scholar 

  • Ensor, D. M.: Prolactin and the primates. In Comparative Endocrinology of Prolactin. Chapman and Hall Ltd, London 1978, pp. 198–201.

  • Ferland, L., G. S. Kledzik, L. Cusan & F. Labrie: Evidence for a role of endorphins in stress-and suckling-induced prolactin release in the rat. Molec. cell Endocr. 1978, 12, 267–272.

    Article  CAS  Google Scholar 

  • Gimenez, T., D. M. Henricks, A. R. Ellicott, C. H. Chang, J. D. Rone & L. W. Grimes: Prolactin and luteinizing hormone (LH) release throughout the postpartum period in the suckled first-calf beef cow. Theriogenology 1980, 14, 135–149.

    Article  CAS  Google Scholar 

  • Haug, E., A. Aakvaag, S. Sunde, K. M. Gautvik & K. B. Erik-Nes: Androgen metabolism and mechanism of action in prolactin secreting rat pituitary cells in culture. Submitted to J. Steroid Biochem.

  • Hurtgen, J. P. & A. D. Leman: Use of PMSG in the prevention of seasonal post-weaning anestrus in sows. Theriogenology 1979, 12, 207–214.

    Article  CAS  Google Scholar 

  • Kann, G., J. Martinet & A. Schirar: Modifications of gonadotrophin secretion during natural and artificial hyperprolactinaemia in the ewe. In P. G. Crosignani & C. Robyn, eds. Prolactin and Human Reproduction. Academic Press, London 1977, pp. 47–59.

  • Landeghem, A. A. J. van & D. F. M. van de Wiel: Radioimmunoassay for porcine prolactin: Plasma levels during lactation, suckling and weaning and after TRH administration. Acta endocr. (Kbh.) 1978, 88, 653–667.

    Google Scholar 

  • Mattheij, J. A. M. & H. J. M. S warts: Circadian variations of the response of plasma prolactin to brief exposure to ether in the male rat. Acta endocr. (Kbh.) 1980, 94, 327–331.

    CAS  Google Scholar 

  • McNeilly, A. S.: Prolactin and the control of gonadotrophin secretion in the female. J. Reprod. Fertil. 1980, 58, 537–549.

    Article  CAS  Google Scholar 

  • Peters, A. R., S. Vyvoda & G. E. Lamming: Comparison of plasma prolactin levels in the milked and suckling cow. J. Endocr. 1979, 83, 27–28,

    Article  Google Scholar 

  • Redshaw, M. R. & S. S. Lynch: An improved method for the preparation of iodinated antigens for radioimmunoassay. J. Endocr. 1974, 60, 527–528.

    Article  CAS  Google Scholar 

  • Smith, B. B. & W. C. Wagner: Lactation physiology of the pig. Proc. 9th Int. Congr. Anim. Reprod., Madrid 1980, vol. III, p. 118.

  • Smith, M. S.: The relative contribution of suckling and prolactin to the inhibition of gonadotropin secretion during lactation in the rat. Biol. Reprod. 1978, 19, 77–83.

    Article  CAS  Google Scholar 

  • Svajgr, A. J., V. W. Hays, G. L. Cromvell & R. H. Dutt: Effect of lactation duration on reproductive performance of sows. J. Anim. Sci. 1974, 38, 100–105.

    Article  CAS  Google Scholar 

  • Taverne, M., A. H. Willemse, S. J. Dieleman & M. Beuers: Plasma prolactin, progesterone and oestradiol-17β concentrations around parturition in the pig. Anim. Reprod. Sci. 1978/79, 1, 257–263.

  • Wiel, D. F. M. van de, A. A. J. van Landeghem, A. H. Willemse & M. M. Bevers: Endocrine control of ovarian function after weaning in the domestic sow. J. Endocr. 1979, 80, 69.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Financial support was given by the Norwegian Agricultural Research Council.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Benjaminsen, E. Plasma Prolactin in the Sow with Emphasis on Variation in Resumption of Ovarian Activity after Weaning. Acta Vet Scand 22, 67–77 (1981). https://doi.org/10.1186/BF03547208

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1186/BF03547208

Keywords