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The Effect of Cysteine and Sodium Selenite on the Toxicity of Cadmium in Staphylococcus Aureus

Effekten av cystein och natriumselenit på kadmiums toxiska inverkan på Staphylococcus aureus

Abstract

Cysteine was shown to have a protective effect on the killing rate caused by cadmium (Cd) but no effect on the uptake of Cd in S. aureus 3719-. The addition of 254 × 10−3 mmol/l of sodium selenite or more into the liquid growth medium increased the lag phase of growth of S. aureus 3719-. Sodium selenite had no protective effect on the toxicity of Cd in S. aureus 3719- as evaluated by the length of the lag phase of growth in the presence of Cd and varying amounts of sodium selenite. 534 × 10−6 mmol/l of sodium selenite in the growth medium had no effect on the uptake of Cd in S. aureus.

Sammanfattning

Resultaten visar att cystein hade en skyddande effekt mot den letala verkan av Cd men ingen inverkan på S. aureus cellernas upptagning av Cd. Tillsatsen av 254 × 10−3 mmol/l natriumselenit eller mera till det flytande näringssubstratet förlängde lagfasen hos S. aureus. Natriumselenit skyddade inte mot Cd:s toxicitet hos S. aureus 3719-. Detta evaluerades genom att mäta lagfasens längd när S. aureus 3719- inkuberades tillsammans med Cd och olika koncentrationer av natriumselenit. 534 × 10−6 mmol/l natriumselenit i näringssubstratet hade inte någon inverkan på upptagningen av Cd hos S. aureus.

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Korkeala, H., Uusi-Rauva, A. & Pekkanen, T.J. The Effect of Cysteine and Sodium Selenite on the Toxicity of Cadmium in Staphylococcus Aureus. Acta Vet Scand 22, 129–136 (1981). https://doi.org/10.1186/BF03547214

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