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Estrone and Progesterone Plasma Levels of Normal Cows and Cows with Parturient Paresis

Plasmanivåer av östron och progesteron hos normala kor och hos kor med puerperal pares

Abstract

Blood plasma concentrations of estrone and progesterone, calcium and inorganic phosphorus were measured in 22 cows (Swedish Red and White Breed) from 4 weeks prepartum up to 6 days post partum. Ten cows with parturient paresis had Ca levels below 6 mg/100 ml. Data from plasma analyses in individual cows were grouped in the following periods: 28–22, 21–15, 14–8, 7–6, 5–4, 3, 2, 1 day(s) before parturition and 1, 2, 3–6 days after parturition. Statistical comparisons of the levels of the hormones and the ratio progesterone/estrone did not reveal any significant differences between the paretic and normal cows at any time period. The results do not support the theories that high systemic levels of estrogens or an imbalance between estrogen and progesterone predispose towards parturient paresis.

Sammanfattning

Koncentrationerna av östron, progesteron, Ca och oorg. P i blodplasma bestämdes på 22 SRB-kor från fyra veckor före partus till sex dagar efter partus. Tio av korna fick puerperal pares med plasma-Ca under 6 mg/100 ml. Resultaten av plasmaanalyserna från enskilda kor sammanfördes inom följande tidsperioder: 28–22, 21–15, 14–8, 7–0, 5–4, 3, 2, 1 dagar före partus och 1, 2, 3–6 dagar efter partus. Statistiska jämförelser av hormonnivåer liksom av kvoterna progesteron/ Östrogen visade inga signifikanta avvikelser vid någon period. Undersökningens resultat stöder ej teorierna om en hog östrogennivå eller en inbalans mellan östrogen och progesteron som predisponerande för puerperal pares hos nötkreatur.

References

  • Bauer, G. C. H., A. Carlsson & B. Lindqvist: Metabolism and homeostatic function of bone. In Mineral Metabolism, Vol. I, Part B. Eds. Gomar & Bronner. Acad. Press, New York 1961.

  • Boilert, B., L.-E. Edqvist, E. D. B. Johansson, P. Lindberg & K. Martinsson: The influence of conjugated estrogens in radioimmunoassays using different antibodies against estradiol-17β. Steroids 1973, 22, 891–894.

    Article  CAS  Google Scholar 

  • Edqvist, L.-E. & E. D. B. Johansson: Radioimmunoassay of oestrone and oestradiol in human and bovine peripheral plasma. Acta endocr. (Kbh.) 1972, 71, 716–730.

    CAS  Google Scholar 

  • Edqvist, L.-E., L. Ekman, B. Gustavsson, L. öhlund, B. Olsson & S. Carstam: The progesterone concentration in blood plasma in cows with parturient paresis. Proc. 11th Nord. Vet. Congr. R 4, Bergen, 1970 a, p. 236.

  • Edquist, L.-E., L. Ekman, B. Gustafsson & G. Åström: Progesterone levels in the bovine peripheral plasma measured by the competitive protein binding technique. Zbl. Vet.-Med. A, 1970 b, 17, 899–908.

    Article  Google Scholar 

  • Edqvist, L.-E., L. Ekman, B. Gustafsson & E. D. B. Johansson: Peripheral plasma levels of oestrogens and progesterone during late bovine pregnancy Acta endocr. (Kbh.) 1972, 72, 81–88.

  • Henricks, D. M., J. F. Dickey, J. R. Hill & W. E. Johnston: Plasma estrogen and progesterone levels after mating, and during late pregnancy and postpartum in cows. Endocrinology 1972, 90, 1336–1342.

    Article  CAS  Google Scholar 

  • Jonsgård, K.: A clinical study on parturient paresis in dairy cows. With special reference to factors related to recovery. Thesis, Oslo 1972, 1–120.

  • Jönsson, G.: On the etiology and pathogenesis of parturient paresis in dairy cows. Statistical and morphological investigations and a review of the literature. Acta agric. scand. 1960, 10, Suppl. 8.

  • Jönsson, G.: Kliniska synpunkter på paresis puerperalis. Begrepps-definitioner. (Clinical aspects on parturient paresis. Definitions). Proc. 11th Nord. Vet. Gongr., Bergen 1970, 76–77.

  • Jönsson, G. & B. Pehrson: Studies on the downer syndrome in dairy cows. Zbl. Vet.-Med. A, 1969, 16, 757–784.

    Article  Google Scholar 

  • Kronfeld, D. S.: Parturient hypocalcemia in dairy cows. In Advances in Veterinary Science and Comparative Medicine. Eds. Brandly and Cornelius. Acad. Press, New York 1971.

  • McLean, F. C. & M. R. Urist: Bone. An introduction to the psysiology of skeletal tissue. Univ. Chicago Press, Chicago 1955.

  • Muir, L. A., J. W. Hibbs, H. R. Conrad & K. L. Smith: Effect of estrogen and progesterone on feed intake and hydroxyproline excretion following induced hypocalcemia in dairy cows. J. Dairy Sci. 1972, 55, 1613–1620.

    Article  CAS  Google Scholar 

  • Payne, J. M., B. F. Sansom & H. W. Symonds: The pathogenesis of milk fever in the dairy cow. In Radioisotopes in Animal Nutrition and Physiology. International Atomic Energy Agency, Vienna 1965, 231–249.

  • Ranney, R. E.: Antagonism between estrone and parathyroid extract in their effects upon bone accretion. Endocrinology 1959, 65, 594–601.

    Article  CAS  Google Scholar 

  • Rendei, J.: Studies of cattle blood groups. II. Blood grouping and parentage tests. Acta agric. scand. 1958, 8, 131–161.

    Google Scholar 

  • Smith, V. G., L. A. Edgerton, H. D. Hafs & E. M. Convey: Bovine serum estrogens, progestins and glucocorticoid during late pregnancy, parturition and early lactation. J. Animal Sci. 1973, 36, 391–398.

    Article  CAS  Google Scholar 

  • Stott, G. H.: Dietary influence on the incidence of parturient paresis. Fed. Proc. 1968, 27, 156–161.

    CAS  PubMed  Google Scholar 

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Supported by grants from the Swedish Council for Forestry and Agricultural Research.

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Edqvist, L.E., Ekman, L., Gustafsson, B. et al. Estrone and Progesterone Plasma Levels of Normal Cows and Cows with Parturient Paresis. Acta Vet Scand 15, 587–596 (1974). https://doi.org/10.1186/BF03547228

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