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A Comparison of Two Dose Levels of Antibiotics for Intramammary Treatment of Clinical Mastitis in Cows

En sammenligning av to doseringsnivå av antibiotika til intramammær behandling αν klinisk mastitt hos ku.

Acta Veterinaria Scandinavica volume 25, pages 151–163 (1984)Cite this article

Abstract

A clinical trial was conducted in Nordre Valdres, Norway, to examine the effect of a low-level vs. a high-level intramammary antibiotic treatment of clinical mastitis. It was also of interest to identify significant risk factors and to estimate the probability of no recovery for given defined levels of risk factors. Quarter milk samples from 166 cows with clinical mastitis were examined before and after treatment, at 3 weeks interval. The two treatment levels did not differ significantly with respect to recovery rate. The probability of no recovery could be estimated by using information on the severity of general clinical signs, lactation number, bacteriological findings, and quarter location.

Sammendrag

Et klinisk forsøk ble utført i Nordre Valdres, Norge, for å undersøke effekten av en lav kontra en høy dosering av intramammser antibiotikabehandling av klinisk mastitt. Av interesse var også å identifisere signifikante riskfaktorer, samt å kunne estimere sannsynligheten for “ikke helbredelse” under gitte definerte nivå a v riskfaktorer. Enkeltspeneprøver fra 166 kyr med klinisk mastitt ble undersøkt før og etter behandling, med tre ukers mellomrom. De to doseringsniváene var ikke signifikant forskjellige med henblikk på helbredelsesprosenten. Beregningene viste videre at dyrets almentilstand, laktasjonsår, bakteriologiske funn, samt lokalisasjon av affisert kjertel virket inn på behandlingsresultatet.

References

  • Bakken, G.: Subclinical mastitis in Norwegian dairy cows. Prevalence rates and epidemiological assessments. Acta agric. scand. 1981, 31, 273–286.

    Google Scholar 

  • Bakken, G. & R. Gudding: The interdependence between clinical and subclinical mastitis. Acta agric. scand. 1982, 32, 17–22.

    Article  Google Scholar 

  • Brown, M. B.: Screening effects in multidimensional contingency tables. Appl. Stat. 1976, 25, 37–46.

    Article  Google Scholar 

  • Dixon, W. J. (ed): BMDP Statistical Software 1981. University of California Press, Berkeley 1981, 727 pp.

  • Feinberg, S. E.: The analysis of Cross-classified Categorical Data. 2nd ed. MIT Press, Cambridge, MA 1980, 198 pp.

  • Kapur, M. P. & R. P. Singh: Treatment of clinical mastitis: a comparison of four different formulations. Indian vet. J., 1978, 55, 320–325.

    Google Scholar 

  • Kingwill, R.: Practical mastitis control. In: Regional Seminar on Bovine Mastitis. School of Veterinary Medicine, University of California, Davis 1978, p. 53–56.

  • Klastrup, O. & P. Schmidt Madsen: Nordiske rekommendationer vedrørende mastitisundersøgelser af kirtelprøver. (Scandinavian recommendations concerning investigation of quarter samples for mastitis). Nord. Vet.-Med. 1974, 26, 197–204.

    CAS  PubMed  Google Scholar 

  • Mercer, H. D., J. N. Geleta, R. A. Baldwin & W. Shimoda: Viewpoint and current concepts regarding accepted and tried products for control of bovine mastitis. J. Amer. vet. med. Ass. 1976, 169, 1104–1114.

    CAS  PubMed  Google Scholar 

  • Newbould, F. H. S.: The use of induced mammary infections for evaluating dry cow treatment products II. Trial of a proposed method to compare three levels of Novobiocin. Canad. J. comp. Med. 1979, 43, 430–433.

    CAS  Google Scholar 

  • Plommet, M. & C. Le Louedec: The role of antibiotic therapy during lactation in the control of clinical and subclinical mastitis. In: F. H. Dodds, T. K. Griffen and R. G. Kingwill (eds) : Proceedings of Seminar on Mastitis Control, April 1975. IDF, Bruxelles 1975, p. 265–281.

  • Tolle, A.: Mastitis — the disease in relation to control methods. In: F. H. Dodds, T. K. Griffen and R. G. Kingwill (eds) : Proceedings of Seminar on Mastitis Control, April 1975, IDF, Bruxelles 1975, p. 3–15.

  • Ziv, G.: Practical pharmacokinetic aspects of mastitis therapy. In: Proceedings of Bovine Mastitis Regional Seminar, April 1978. School of Veterinary Medicine, University of California, Davis 1978, p. 1–52.

  • Ziv, G.: Drug selection and use in mastitis: Systemic vs local therapy. J. Amer. vet. med. Ass. 1980, 176, 1109–1115.

    CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. National Veterinary Institute, Oslo, Norway

    J. Bjorland, G. Bakken, R. Eidsaa, T. B. Farver, L. Homme, N. Leine & E. Onstad

  2. Department of Epidemiology and Preventive Medicine, University of California, Davis, USA

    J. Bjorland, G. Bakken, R. Eidsaa, T. B. Farver, L. Homme, N. Leine & E. Onstad

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  1. J. Bjorland
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  2. G. Bakken
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  3. R. Eidsaa
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  4. T. B. Farver
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  5. L. Homme
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  6. N. Leine
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  7. E. Onstad
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Bjorland, J., Bakken, G., Eidsaa, R. et al. A Comparison of Two Dose Levels of Antibiotics for Intramammary Treatment of Clinical Mastitis in Cows. Acta Vet Scand 25, 151–163 (1984). https://doi.org/10.1186/BF03547261

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Acta Veterinaria Scandinavica

ISSN: 1751-0147