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Calcium Effects on Renal Conservation of Magnesium in Cows

Innvirkning av kalsium på nyrekonserveringen aν magnesium hos kyr.

Abstract

Urinary excretion rates for Ca, Mg and P were compared to simultaneous measurements of the same elements in blood plasma of cows recovering from moderate hypocalcaemia post partum and in 1 animal during recovery from hypocalcaemia induced by fasting.

The renal conservation of Mg was found to be increased during the hypocalcaemia, theoretical tubular reabsorption rates being correlated to plasma Ca with r = –0.7, P < 0.001. The relationship was observed in the plasma Ca range from about 2.0 to 2.6 mmol/1.

The findings may explain the occurrence of hypermagnesaemia in hypocalcaemic cows and the delay in the development of hypo-magnesaemia seen in cows with fasting-induced hypocalcaemia.

Sammendrag

Mengder av Ca, Mg og Ρ utskilt per tidsenhet med urinen ble sammenholdt med samtidige konsentrasjoner av de 3 elementer i blodplasma fra kyr i løpet av normaliseringsperioden etter moderat hypokalsemi post partum og i et tilfelle etter fremkalling av hypokalsemi ved faste.

Nyrekonserveringen av Mg viste seg å vaere økt under hypokalsemi. Teoretiske tubulære reabsorpsjonshastigheter for elementet var korrelert til plasma Ca (interval ca. 2.0–2.6 mmol/1) med r = – 0.7, Ρ < 0.001.

Funnene kan forklare forekomsten av hypermagnesemi hos hypokalsemiske kyr og forsinkelsen i utviklingen a v hypomagnesemi hos kyr med hypokalsemi etter faste.

References

  • Alcock, N. & I. MacIntyre: Interrelation of calcium and magnesium absorption. Clin. Sci. 1962, 22, 185–193.

    CAS  PubMed  Google Scholar 

  • Barker, E. S., J. R. Elkinton & J. K. Clark: Studies of the renal excretion of magnesium in man. J. clin. Invest. 1959, 38, 1733–1745.

    Article  CAS  Google Scholar 

  • Burnatowska, M. A., C. A. Harris, R. A. L. Sutton & J. A. Dirks: Effects of PTH and cAMP on renal handling of calcium, magnesium and phosphate in the hamster. Amer. J. Physiol. 1977, 233, 514–518.

    Google Scholar 

  • Care, A. D. & A. Th. van’t Klooster: In vivo transport of magnesium and other cations across the wall of the gastro-intestinal tract of sheep. J. Physiol. 1965, 177, 174–191.

    Article  CAS  Google Scholar 

  • Dirks, J. H. & G. A. Quamme: Renal handling of magnesium. Advanc. exp. Med. Biol. 1978, 103, 51–64.

    Article  CAS  Google Scholar 

  • Dishington, I. W.: Prevention of milk fever (hypocalcaemic paresis puerperalis) by dietary salt supplements. Acta vet. scand. 1975, 16, 503–512.

    Article  CAS  Google Scholar 

  • Ebel, H. & T. Günther: Magnesium metabolism: A review. J. clin. Chem. clin. Biochem. 1980, 18, 257–270.

    CAS  PubMed  Google Scholar 

  • Ender, F., Inger W. Dishington, A. Helgebostad & E. Martinsons: The magnesium problem in relation to the tetany-paresis syndrome in dairy cows. Nord. Vet.-Med. 1957, 9, 881–917.

    Google Scholar 

  • Halse, K.: Apparent strengthening of calcium homeostasis in cows by starvation of short duration. Nord. Vet.-Med. 1958, 10, 9–16.

    Google Scholar 

  • Halse, K.: Changes in serum calcium and magnesium in cows subjected to short periods of fasting. Proc. VIII. Intern. Grassland Congr., Reading, Berkshire, England, 1960. The Alden Press, Oxford, 1961, p. 553–558.

  • Halse, K.: Individual variation in blood magnesium and susceptibility to hypomagnesaemia in cows. Acta vet. scand. 1970, 11, 394–414.

    CAS  PubMed  Google Scholar 

  • Hove, K., R. L. Horst & E. T. Littledike: Effects of 1α-Hydroxyvitamin D3, 1,25-Dihydroxyvitamin D2, 1,24,25-Trihydroxyvitamin D3, and 1,25,26-Trihydroxyvitamin D3 on mineral metabolism and 1,25 Dihydroxyvitamin D concentrations in dairy cows. J. Dairy Sci. 1983, 66, 59–66

  • Jonsgård, K.: A clinical study on parturient paresis in dairy cows, with special reference to factors related to recovery. Thesis. The Veterinary College of Norway, Oslo, 1972, 120 pp.

  • Kolb, E.: Lehrbuch der Physiologie der Haustiere. (Textbook of physiology of domestic animals). Gustav Fisher Verlag, Jena, 1962, 942 pp.

  • Marr, A., E. W. Moodie & A. Robertson: Some biochemical and clinical aspects of milk fever. J. comp. Path. 1955, 65, 347–365.

    Article  CAS  Google Scholar 

  • Nordin, B. E. C.: Calcium, phosphate and magnesium metabolism. Clinical physiology and diagnostic procedures. Publ. Churchill Livingstone, Edinburgh-London-New York, 1976, 683 pp.

  • Quamme, G. A.: Effect of hypocalcaemia on renal tubular handling of calcium and magnesium. Canad. J. Physiol. Pharmacol. 1982, 60, 1275–1280.

    Article  CAS  Google Scholar 

  • Richardson, J. A. & L. G. Welt: The hypomagnesaemia of vitamin D administration. Proc. Soc. exp. Biol. Med. 1965, 118, 512–514.

    Article  CAS  Google Scholar 

  • Ringbom, A.: Complexation in Analytical Chemistry. Interscience Publishers, N. Y./London 1963, 395 pp.

  • Rouffignac, C. de, B. Corman & N. Roinel: Stimulation by antidiuretic hormone of electrolyte tubular reabsorption in rat kidney. Amer. J. Physiol. 1983, 244, F156–164.

  • Samiy, A. H. E., J. L. Brown, D. L. Globus, R. H. Kessler & D. D. Thompson: Interrelation between renal transport systems of magnesium and calcium. Amer. J. Physiol. 1960, 198, 599–602.

    Article  CAS  Google Scholar 

  • Sjollema, B.: Stoffwechselstörungen des Rindes. Zusammenfassender Bericht. (Metabolic disturbances of cattle. Summarizing report.). Acta vet. neerlandica 1933, Tome I — Fasc. II. 127 pp.

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Halse, K. Calcium Effects on Renal Conservation of Magnesium in Cows. Acta Vet Scand 25, 213–228 (1984). https://doi.org/10.1186/BF03547266

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