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Swine Dysentery: The Influence of Dietary Selenium on Clinical and Pathological Effects of Treponema Hyodysenteriae Infection
Svinedysenteri: Virkningen av forskjellige niuåer av seien i dietten på de kliniske og patologiske utslag av infeksjon med Treponema hyodysenteriae.
Acta Veterinaria Scandinavica volume 25, pages 1–9 (1984)
Abstract
Twenty-four conventionally reared pigs divided into 4 groups were fed a basic ration deficient in selenium. The following daily supplement of selenium was given per pig; Group 1: none, group 2: 0.2 mg, group 3: 0.4 mg and group 4: 0.8 mg. After 51 days all pigs were inoculated orally with a pure culture of Treponema hyodysenteriae, and subsequently observed for 26 days. Clinical signs of swine dysentery were seen in all 4 groups. Criteria such as morbidity rate, incubation time and weight gain showed that the non-supplemented pigs suffered more severely from swine dysentery than the supplemented ones. Best protection was found among the pigs given a daily supplement of 0.4 mg selenium, whereas a supplement of 0.8 mg had a negative influence on the resistance to swine dysentery. The results indicate that selenium plays a more complex role in mucosal defence mechanisms than hitherto anticipated.
Sammendrag
Tjuefire vanlig oppdrettede griser ble delt i fire grupper og gitt et selenfattig grunnfór. Følgende daglige tilskudd av seien ble gitt til hver gris: gruppe 1: 0, gruppe 2: 0.2 mg, gruppe 3: 0.4 mg og gruppe 4: 0.8 mg. Etterat grisene var blitt fóret med de forskjellige diettene i 51 dager ble de podet med en renkultur av T. hyodysenteriae pr. os. og deretter observert i 26 dager. Kliniske symptomer på svinedysenteri ble sett i alle fire gruppene. Registreringer vedrørende morbiditet, inkubasjonstider og tilvekst viste at grisene uten tilskudd av seien hadde en mer alvorlig form av svinedysenteri enn de som fikk tilskudd. Den beste beskyttelsen mot infeksjon med T. hyodysenteriae ble sett hos griser med et daglig tilskudd på 0.4 mg seien. Et daglig tilskudd pä 0.8 mg seien hadde en negativ virkning på resistenten mot svinedysenteri. Disse resultater kan derfor tyde på at seien spiller en mer kompleks rolle i tarmslimhinnens forsvarsmekanismer enn man hittil har vaert klar over.
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Teige, J., Larsen, H.J. & Tollersrud, S. Swine Dysentery: The Influence of Dietary Selenium on Clinical and Pathological Effects of Treponema Hyodysenteriae Infection. Acta Vet Scand 25, 1–9 (1984). https://doi.org/10.1186/BF03547273
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DOI: https://doi.org/10.1186/BF03547273