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Peripheral Plasma Levels of Estrone And Progesterone in Pregnant Pigs Treated with Dexamethasone

Blodplasmanivåer av östron och progesteron hos dräktiga grisar behandlade med dexametason

Abstract

Five pregnant pigs of the Swedish Landrace Breed were treated with dexamethasone i.m. injections during early and late pregnancy. The daily dose of dexamethasone was never more than 100 mg. There were no significant changes in the maternal plasma levels of estrone and progesterone during dexamethasone injections. The dexamethasone initiated neither abortion nor parturition.

Sammanfattning

Fem dräktiga grisar (Svensk Lantras) behandlades under tidig och sen dräktighet med intramuskulära injektioner av dexametason. Den dagliga dosen dexametason överskred aldrig 100 mg. Inga signifikanta förändringar av plasmanivåerna av östron och progesteron kunde ses i samband med behandlingarna. Dexametasonet initierade varken abort eller prematur förlossning.

References

  • Ash, R. W., P. G. Banks, G. Bailes, S. Broad & R. P. Heap: Plasma estrogen, progesterone and corticosteroid concentrations in the pregnant, parturient and lactating sow. J. Reprod. Fertil. 1973, 33, 359–360.

    Article  CAS  Google Scholar 

  • Edqvist, L.-E. & E. D. B. Johansson: Radioimmunoassay of estrone and estradiol in human and bovine peripheral plasma. Acta endocr. (Kbh.) 1972, 71, 716–730.

    CAS  Google Scholar 

  • Edqvist, L.-E., L. Ekman, B. Gustafsson, S.-O. Jacobsson, E. D. B. Johansson & J.-O. Lindell: Peripheral plasma levels of estrone and progesterone in pregnant cows treated with dexamethasone. Acta endocr. (Kbh.) 1972, 71, 731–742.

    CAS  Google Scholar 

  • Fulling, P.: Premature parturition following dexamethasone administration to pregnant ewes. Acta endocr. (Kbh.) 1970, 66, 289–295.

    Google Scholar 

  • Johansson, E. D. B.: Progesterone levels in peripheral plasma during the luteal phase of the normal menstrual cycle measured by a rapid competitive protein binding technique. Acta endocr. (Kbh.) 1969, 61, 607–617.

    CAS  Google Scholar 

  • Johansson, I. & J. Rendei: Ärftlighet och husdjursförädling. (Heredity and animal breeding). LT:s Förlag, Stockholm 1963.

  • Killian, D. B., H. A. Garverick & B. N. Day: Peripheral plasma progesterone and corticoid levels at parturition in the sow. J. Animal Sci 1972, 35, 1119.

  • Molokwu, E. C. I. & W. C. Wagner: Endocrine physiology of the puerperal sow. J. Animal Sci. 1973, 36, 1158–1163.

    Article  CAS  Google Scholar 

  • North, S. A., E. R. Hauser & N. L. First: Induction of parturition in swine and rabbits with the corticosteroid dexamethasone. J. Animal Sci. 1973, 36, 1170–1173.

    Article  CAS  Google Scholar 

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This study was supported by the Swedish Council for Forestry and Agricultural Research and the Ford Foundation.

The following abbreviations and trivial names are used : Dexamethasone : 9α-fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, Estrone : 3-hydroxy-1,3,5 (10) -estratriene-17-one, Progesterone : 4-pregnene-3,20-dione, s: Standard deviation

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Bosu, W.T.K., Edqvist, LE. & Gustafsson, B. Peripheral Plasma Levels of Estrone And Progesterone in Pregnant Pigs Treated with Dexamethasone. Acta Vet Scand 15, 111–119 (1974). https://doi.org/10.1186/BF03547498

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