Skip to main content
  • Published:

Fetal Infection with Porcine Parvovirus in Herds with Reproductive Failure

Infektion med porcint parvovirus i fostre fra besætninger med reproduktionsproblemer

Abstract

During a 20 months period in 1978 and 1979 aborted, macerated and mummified fetuses as well as stillborn piglets from herds with reproductive failure were examined for evidence of infection with porcine parvovirus (PPV). A total of 602 cases were examined and evidence of infection with PPV was found in 269 (45 %). In 52 % of these antibody to PPV was found. Infective PPV as well as antibody to PPV were found in 41 %, whereas infective PPV alone was found in 7 %. When abortions were excluded from the results a high prevalence of infection with PPV (73–90 %) was found among fetuses of all sizes with the exception of fetuses dead late in gestation or at term.

Sammendrag

Over en 20 måneders periode i 1978 og 1979 blev aborterede, macererede og mumificerede fostre samt døde fuldbårne grise fra besætninger med reproduktionsproblemer undersøgt for infektion med porcint parvovirus (PPV). Iait blev 602 tilfælde undersøgt, og infektion med PPV blev påvist i 269 (45 %). I 52 % af disse fandtes antistof mod PPV. Infektivt PPV samt antistof mod PPV fandtes i 41 %, medens infektivt PPV alene fandtes i 7 %. Når aborterne blev udelukket fra undersøgelsesresultaterne, fandtes infektion med PPV i en stor procentdel (73–90 %) af fostre i alle størrelser med undtagelse af fostre døde sent i drægtighedsperioden eller ved fødslen.

References

  • Anon.: Svineavl og -produktion i Danmark 1979. (Swine breeding and production in Denmark 1979). Landsudvalget for svineavl og -produktion, Andelsslagteriernes fælleskontor, Axelborg, Copenhagen 1979, p. 36.

  • Bille, N., N. C. Nielsen, J. L. Larsen & J. Svendsen: Preweaning mortality in pigs. Nord. Vet.-Med. 1974, 26, 294–313.

    CAS  PubMed  Google Scholar 

  • Binns, R. M.: Bone marrow and lymphoid cell injection of the pig foetus resulting in transplantation tolerance or immunity, and immunoglobulin production. Nature (Lond.) 1967, 214, 179–181.

    Article  CAS  Google Scholar 

  • Bourne, F. J., J. Curtis, R. H. Johnson & D. F. Collings: Antibody formation in porcine fetuses. Res. Vet. Sci. 1974, 16, 223–227.

    Article  CAS  Google Scholar 

  • Cartwright, S. F. & R. A. Huck: Viruses isolated in association with herd infertility, abortions and stillbirths in pigs. Vet. Rec. 1967, 81, 196–197.

    Google Scholar 

  • Cropper, M., H. W. Dunne, A. D. Lemon, A. L. Starkey & D. C. Hoefling: Prevalence of antibodies to porcine enteroviruses and porcine parvovirus in body fluids of fetal pigs from small vs large litters. J. Amer. vet. med. Ass. 1976, 168, 233–235.

    CAS  PubMed  Google Scholar 

  • Cutlip, R. C. & W. L. Mengeling: Pathogenesis of in utero infection: Experimental infection of eight- and ten-week-old porcine fetuses with porcine parvovirus. Amer. J. vet. Res. 1975, 36, 1751–1754.

    CAS  PubMed  Google Scholar 

  • Donaldson-Wood, C. R., H. S. Joo & R. H. Johnson: The effect on reproductive performance of porcine parvovirus infection in a susceptible pig herd. Vet. Rec. 1977, 100, 237–239.

    Article  CAS  Google Scholar 

  • Fennestad, K. L., C. Borg-Petersen & E. Brummerstedt: Leptospira antibody formation by porcine foetuses. Res. Vet. Sci. 1968, 9, 378–380.

    Article  CAS  Google Scholar 

  • Forman, A. J., C. Lenghaus, G. G. Hogg & C. J. Hale: Association of a parvovirus with an outbreak of foetal death and mummification in pigs. Aust. vet. J. 1977, 53, 326–329.

    Article  CAS  Google Scholar 

  • Gillick, J. C: An outbreak of swine foetal mummification associated with porcine parvovirus. Aust. vet. J. 1977, 53, 105–106.

    Article  CAS  Google Scholar 

  • Horner, G. W. & R. Hunter: Isolation of porcine parvovirus from aborted piglets. N. Z. vet. J. 1977, 25, 25–26.

    Article  CAS  Google Scholar 

  • Johnson, R. H.: A search for parvoviridae (Picodnaviridae). Vet. Rec. 1969, 84, 19–20.

    Article  CAS  Google Scholar 

  • Johnson, R. H.: Isolation of swine parvovirus in Queensland. Aust. vet. J. 1973, 49, 157–159.

    Article  CAS  Google Scholar 

  • Joo, H. S., C. R. Donaldson-Wood & R. H. Johnson: Observations on the pathogenesis of porcine parvovirus infection. Arch. Virol. 1976a, 51, 123–129.

  • Joo, H. S., C. R. Donaldson-Wood & R. H. Johnson: Rapid diagnostic techniques for detection of porcine parvovirus infection in mummified foetuses. Aust. vet. J. 1976b, 52, 51–52.

  • Joo, H. S., C. R. Donaldson-Wood, R. H. Johnson & R. S. F. Cambell: Pathogenesis of porcine parvovirus infection: Pathology and immunofluorescence in the foetus. J. comp. Path. 1977, 87, 383–391.

    Article  CAS  Google Scholar 

  • Joo, H. S. & R. H. Johnson: Observations on rapid diagnosis of porcine parvovirus in mummified foetuses. Aust. vet. J. 1977, 53, 106–107.

    Article  CAS  Google Scholar 

  • Lei, J. C., E. Overby, M. Holm Jensen & F. O. Sørensen: Preparation of a porcine parvovirus vaccine. Proc. Int. Pig Vet. Soc. Congr., Copenhagen 1980, p. 64.

  • Mengeling, W. L.: Prevalence of porcine parvovirus-induced reproductive failure: An abattoir study. J. Amer. vet. med. Ass. 1978, 172, 1291–1294.

    CAS  PubMed  Google Scholar 

  • Mengeling, W. L.; Prenatal infection following maternal exposure to porcine parvovirus on either the seventh or fourteenth day of gestation. Canad. J. comp. Med. 1979, 43, 106–109.

  • Mengeling, W. L. & R. C. Cutlip: Pathogenesis of in utero infection: Experimental infection of five-week-old porcine fetuses with porcine parvovirus. Amer. J. vet. Res. 1975, 36, 1173–1177.

    CAS  PubMed  Google Scholar 

  • Mengeling, W. L. & R. C. Cutlip: Reproductive disease experimentally induced by exposing pregnant gilts to porcine parvovirus. Amer. J. vet. Res. 1976, 37, 1393–1400.

    CAS  PubMed  Google Scholar 

  • Mengeling, W. L., R. C. Cutlip, R. A. Wilson, J. B. Parks & R. F. Marshall: Fetal mummification associated with porcine parvovirus infection. J. Amer. vet. med. Ass. 1975, 166, 993–995.

    CAS  PubMed  Google Scholar 

  • Mengeling, W. L., P. S. Paul & T. T. Brown: Transplacental infection and embryonic death following maternal exposure to porcine parvovirus near the time of conception. Arch, virol. 1980, 65, 55–62.

    Article  CAS  Google Scholar 

  • Morimoto, T., Y. Fujisaki, Y. Ito & Y. Tanaka: Biological and physicochemical properties of porcine parvovirus recovered from stillborn piglets. Nat. Inst. Anim. Hlth Quart. 1972, 12, 137–144.

    CAS  Google Scholar 

  • Nielsen, H. E. & H. J. Bendixen: Undersøgelser over fosterdød hos svin. (Foetal death in swine). Landøk. Forsøgslab. Årbog. Copenhagen 1969, p. 23–32.

  • Rodeffer, H. E., A. D. Leman, H. W. Dunne, M. Cropper & D. J. Sprecker: Reproductive failure in swine associated with maternal seroconversion for porcine parvovirus. J. Amer. vet. med. Ass. 1975, 166, 991–992.

    CAS  PubMed  Google Scholar 

  • Rondhuis, P. R. & P. J. Straver: Enige kenmerken van een klein, hemagglutinerend DNA-virus, geisoleerd uit een verworpen varkensfoetus. (Some properties of a small haemagglutinating DNA-virus, isolated from an aborted fetus of a pig). Tijdschr. Diergeneeskd. 1972, 97, 1257–1267.

    CAS  Google Scholar 

  • Sørensen, K. J., J. Askaa & K. Dalsgaard: Assay for antibody in pig fetuses infected with porcine parvovirus. Acta vet. scand. 1980, 21, 312–317.

    Article  Google Scholar 

  • Wrathall, A. E.: Reproductive Disorders in Pigs. Review series No. 11 of the Commonwealth Bureau of Animal Health, Commonwealth Agricultural Bureuax, 1975.

  • Wrathall, A. E. & W. L. Mengeling: Effect of transferring parvovirusinfected fertilized pig eggs into seronegative gilts. Br. vet. J. 1979, 135, 255–261.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sørensen, K.J., Askaa, J. Fetal Infection with Porcine Parvovirus in Herds with Reproductive Failure. Acta Vet Scand 22, 162–170 (1981). https://doi.org/10.1186/BF03547505

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1186/BF03547505

Keywords