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Swine Dysentery: A Scanning Electron Microscopic Investigation

Svinedysenteri: En skanning elektron-mikroskopisk undersøkelse

Acta Veterinaria Scandinavica volume 22, pages 218–225 (1981)Cite this article

Abstract

An investigation by scanning electron microscope was performed on colonic specimens from 4 conventionally reared pigs, 2 of which were suffering from swine dysentery (SD) after inoculation with Treponema hyodysenteriae in pure culture. In pigs with SD dilated cryptal openings surrounded by uneven mucosa with furrows and ridgeformations were found in areas with scattered pseudomembranes. The treponemes were numerous on the mucosal surface but seemed only to penetrate damaged epithelial cells. Freeze-fractured sections from the same pigs revealed dilated crypts where the microvilli were short, irregular and markedly reduced in number possibly due to change in cell kinetics. The present study seems to indicate that epithelial attachment and penetration of treponemes are of minor importance in SD pathogenesis.

Sammendrag

Det er utført en skanning elektron-mikroskopisk undersøkelse av kolonprøver fra 4 konvensjonelt oppdrettede griser. To av dyrene hadde utviklet svinedysenteri etter poding med en renkultur av Treponema hyodysenteriae. Hos disse to grisene kunne det i områder med spredte pseudomembraner sees dilaterte kjertelåpninger omgitt av en ujamn slimhinne med furer og små kamdannelser. Treponema-bakterier var tallrike på slimhinneoverflaten og de syntes bare å penetrere skadete epitelceller. Fryse-frakturerte snitt fra de samme grisene viste dilaterte kjertier hvor det var korte uregelmessige mikrovilli som var sterkt reduserte i antall. Dette sistnevnte forholdet antas å skyldes forandringer i cellekinetikken. Denne undersøkelsen synes å indikere at epitelial tilheftning og penetrasjon av treponema-bakterier er av liten betydning for patogenesen ved svinedysenteri.

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Authors and Affiliations

  1. National Veterinary Institute, Dep., Oslo 1, P.O. Box 8156, Oslo, Norway

    Jon Teige Jr., Thor Landsverk, Arve Lund & Hans Jørgen Larsen

  2. Department of Pathology and Department of Microbiology and Immunology, Veterinary College of Norway, Oslo, Norway

    Jon Teige Jr., Thor Landsverk, Arve Lund & Hans Jørgen Larsen

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  1. Jon Teige Jr.
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  2. Thor Landsverk
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  3. Arve Lund
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Teige, J., Landsverk, T., Lund, A. et al. Swine Dysentery: A Scanning Electron Microscopic Investigation. Acta Vet Scand 22, 218–225 (1981). https://doi.org/10.1186/BF03547511

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Acta Veterinaria Scandinavica

ISSN: 1751-0147