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Ovine White-Liver Disease (OWLD). Trace Elements in Liver

Kvitleversjuke (kobolt/vitamin Β12 mangel) hos lam. Sporstoffinnhold i leveren

Acta Veterinaria Scandinavica volume 31, pages 297–307 (1990)Cite this article

Abstract

Trace elements in liver were examined in vitamin B12 deficient lambs which developed ovine white-liver disease (OWLD), in cobalt/ vitamin B12 supplemented lambs on the same pastures as well as clinically healthy, but sometimes subclinical B12 deficient lambs on other pastures (H). Liver Co was marginal to deficient in both OWLD lambs (S lambs) and H lambs. Supplementation with B12 or Co elevated liver Co. Liver copper was significantly lower in OWLD lambs than in the H lambs, and Co/B12 supplementation on pasture generally had no significant effect on the contents. Dosing lambs on OWLD pastures with copper oxide needles (SCuO), however, resulted in high/toxic liver Cu. Dosing with Co, Se and Cu glass boluses resulted in adequate liver Cu, except for 1 lamb with toxic amounts indicating dissolution and absorption of the bolus. OWLD lambs had significantly lower liver molybdenum than H lambs, and Co/B12 supplementation elevated values, while CuO treatment depressed them. Liver zinc, manganese and selenium are also reported.

Sammendrag

Sporstoffinnholdet i leveren ble undersøkt hos vitamin B12-deficitte lam som utviklet kvitleversjuke (OWLD, S-lam), hos lam som gikk på de samme beitene men ble dosert med kobolt/-vitamin Β12, og hos klinisk friske som gikk på andre beiter, men som enkelte år var subklinisk B12 deficitte (Η-lam). Koboltinnholdet i leveren var marginalt til deficitt både hos lam med kvitleversjuke (S) og Η-lam. Behandling med vitamin B12 eller ekstra tilskud av kobolt økte innholdet av Co i leveren. Innholdet av kopper var signifikant lavere hos OWLD affiserte lam, og Co/B12 behandling av lam på disse beitene så ikke ut til å øke innholdet. Dosering med kopperoksydnåler resulterte i svært høye/toksiske nivå av Cu i leveren. Dosering med kobolt/selen/kopper glassboli resulterte i adekvat kopperinnhold, bortsett fra ett lam som hadde toksiske mengder, noe som tydet på oppløsning og absorbsjon av bolus. Lam med kvitleversjuke hadde signifikant lavere innhold av molybden i leveren enn H-lamma, og Co/B12 behandling resulterte i økning av innholdet, mens kopperbehandling førte til en senkning. Innholdet av sink, mangan og selen er også oppgitt.

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  1. State Veterinary Research Station for Small Ruminants, P. O. Box 264, N-4301, Høyland, Sandnes, Norway

    Martha J. Ulvund

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Ulvund, M.J. Ovine White-Liver Disease (OWLD). Trace Elements in Liver. Acta Vet Scand 31, 297–307 (1990). https://doi.org/10.1186/BF03547542

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Acta Veterinaria Scandinavica

ISSN: 1751-0147