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Bone Mineral Determination in Coccygeal Vertebrae by Dichromatic Photon Absorptiometry*

Benmineralmätningar utförda med dikromatisk foton absorptiometri i svanskotor hos nötkreatur

Acta Veterinaria Scandinavica volume 19, pages 1–17 (1978)Cite this article

Abstract

A bone scanning device for determination of the bone mineral content in coccygeal vertebrae of cattle is described. The equipment has two gamma radiation sources, consisting of 125I and 241Am with energies of 27 and 60 keV, respectively. Absorption is measured by a scintillator photomultiplier detector. The precision of the method has been tested in vivo and found satisfactory (1.5%). It is therefore well suited for measuring bone mineral content in coccygeal vertebrae, and thereby the changes which take place in mineral content can be followed.

Sammanfattning

Den kortvågiga, elektromagnetiska strålningens absorption i ben och mjukdelar är dels beroende av den energi fotonen har, dels vävnadens kemiska sammansättning. Om fotonen har en given energi blir absorptionen enbart beroende av vävnadens sammansättning och mängd. Den teknik som här användes bygger på absorption av fotoner med skilda våglängder, 27 keV (125J) resp. 60 keV (241Am).

Absorptionen i benvävnad och mjukvävnad är en funktion av fotonens energi. Vid en given mängd benvävnad/mjukvävnad förhåller sig absorptlonskurvorna tili varandra på ett speciellt sätt. Vid en ändrad mängd benvävnad/mjukvävnad blir kurvorna annorlunda, men aldrig parallella. Genom att jämföra absorptionen vid olika energinivåer kan alltså absorptionen i ben- respektive mjukvävnad bestämmas. Därav följer att mängden benvävnad i ett Objekt kan uppmätas.

Mätutrustningen består av en strålkälla, en detektör, en scanner, en elektronisk kalkylator (Bone Scanner 7102, AB Atomenergi, Studsvik, Nyköping, Sweden), en skrivare, en printer och en speciellt konstruerad hallare. Strålkällan utgörs av 125J (25 mGi) och 241Am (10 mCi). Detektorn består av en scintillator med en NaJ-kristall. Scannerns konstruktion möjliggör mätning i vertikal och horisontal riktning. Mätningen utföres på svanskotor, och den speciella hallaren är konstruerad för fixering av svansen. Vanligen mätes två kotor under epidural anestesi. Mätningarna göres vinkelrätt mot och stegvis längs kotornas longitudinella axel. Mätningarna börjar vid den disk som ligger närmast kaudalt om de två kotorna. 15—18 „ scans” görs på varje kota. Summan av erhållna värden för varje „scan” anger kvantiteten benmineral i den eller de mätta kotorna. Metodfelet har fastställts genom upprepade mätningar av en standard bestående av en Al-legering samt genom upprepade mätningar av svanspreparat och svansar på levande nötkreatur. Metodfelet vid mätningarna av två svanskotor befanns vara 1.5 %.

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Authors and Affiliations

  1. The Department of Animal Hygiene and the Department of Clinical Radiology, Animal Science Centre, College of Veterinary Medicine, Swedish University of Agricultural Sciences, S-750 07, Uppsala 7, Sweden

    Roland Zetterholm & Nils Dalén

  2. Department of Orthopedic Surgery, Karolinska Sjukhuset, Stockholm, Sweden

    Roland Zetterholm & Nils Dalén

  3. Laboratory for Comparative Orthopaedics, Hospital for Special Surgery, USA

    Roland Zetterholm & Nils Dalén

  4. New York Hospital — Cornell University Medical College, New York, USA

    Roland Zetterholm & Nils Dalén

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  1. Roland Zetterholm
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  2. Nils Dalén
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Zetterholm, R., Dalén, N. Bone Mineral Determination in Coccygeal Vertebrae by Dichromatic Photon Absorptiometry*. Acta Vet Scand 19, 1–17 (1978). https://doi.org/10.1186/BF03547637

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Acta Veterinaria Scandinavica

ISSN: 1751-0147