Skip to main content

A Case of Neospora Associated Bovine Abortion in Sweden


Neospora caninum is a recently recognized protozoan organism that causes fatal neuromuscular disease in dogs and abortions and stillbirths in cattle and other animals (Dubey & Lindsay 1993). The parasite is morphologically similar and phylogenetically very closely related to the cyst-forming coccidium Toxoplasma gondii (Ellis et al. 1994, Holmdahl et al. 1994). This group of parasites has a two-host life cycle principally involving a carnivorous definitive host and a herbivorous or omnivorous intermediate host. However, with N. caninum, there is as yet no knowledge of any definitive host harbouring sexual stages of the parasite. The only known route of transmission is vertical from mother to foetus (Dubey & Lindsay 1993).


  • Björkman C, LundénA, Holmdahl J, Barber J, Trees AJ, Uggla A: Neospora caninum in dogs: Detection of antibodies by ELISA using an iscom antigen. Parasite Immunol. 1994, 16, (643–648).

    Article  Google Scholar 

  • Dubey JP, HattelAL, Lindsay DS, Topper MJ: Neonatal Neospora caninum infection in dogs: Isolation of the causative agent and experimental transmission. J. Amer. vet. med. Assoc. 1988, 193, (1259–1263).

    CAS  Google Scholar 

  • Dubey JP, Lindsay DS: Neosporosis. Parasitol. Today 1993, 9, (452–458).

    Article  CAS  Google Scholar 

  • Ellis J, Luton K, Baverstock PR, Brindley PJ, Nimmo KA, Johnson AM: The phylogeny of Neospora caninum. Mol. biochem. Parasitol. 1994, 64, (303–311).

    Article  CAS  Google Scholar 

  • Holmdahl OJM, Mattsson JG, Uggla A, Johansson K-E: The phylogeny of Neospora caninum and Toxoplasma gondii based on ribosomal RNA sequences. FEMS Microbiol. Lett. 1994, 119, (187–192).

    Article  CAS  Google Scholar 

  • Lindsay DS, Dubey JP: Immunohistochemical diagnosis of Neospora caninum in tissue sections. Amer. J. vet. Res. 1989, 50, (1981–1983).

    CAS  PubMed  Google Scholar 

  • Thilsted JP, Dubey JP: Neosporosis-like abortion in a herd of dairy cattle. J. vet. diagn. Invest. 1989, 1, (205–209).

    Article  CAS  Google Scholar 

  • Uggla A, Dubey JP, Lundmark G, Olson P: Encephalomyelitis and myositis in a boxer puppy due to a Neospora-like infection. Vet. Parasitol. 1989, 32, (255–260).

    Article  CAS  Google Scholar 

  • Uggla A, Sjöland L, Dubey JP: Immunohistochemical diagnosis of toxoplasmosis in fetuses and fetal membranes of sheep. Amer. J. vet. Res. 1987, 48, (348–351).

    CAS  PubMed  Google Scholar 

Download references


This study was supported by the Ivar and Elsa Sandberg Foundation and the Swedish Council for Forestry and Agricultural Research. The assistance and advice of Katarina Gustafsson, Jens G Mattsson, Per Olle Nilsson, Jan Persson and Susanne Stenlund are gratefully acknowledged. The study was part of the EU research collaboration COST 820.

Author information

Authors and Affiliations


Rights and permissions

Reprints and Permissions

About this article

Cite this article

Holmdahl, O.J.M., Björkman, C. & Uggla, A. A Case of Neospora Associated Bovine Abortion in Sweden. Acta Vet Scand 36, 279–281 (1995).

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: