Skip to main content
Download PDF
  • Brief Communication
  • Published:

Prostaglandin F2α Metabolite Levels Following an Embryo Transfer Procedure in the Mare

Acta Veterinaria Scandinavica volume 36, pages 145–147 (1995)Cite this article

Abstract

Hormonal, chemical, and mechanical stimuli can activate the arachidonic acid cascade and result in formation of prostaglandins and related substances. These compounds can have a profound role in the initiation of the inflammatory process (Higgins & Lees 1984). Prostaglandin (PG) F2α is the key hormone in reproductive physiology with well-known effects on reproductive performance e.g. luteolysis and abortion. An activation of the arachidonic acid cascade, caused by mechanical manipulation during an embryo transfer procedure, might be one explanation for early embryonic loss.

References

  • Bowen MJ, Salsbury JM, Bowen JM, Kraemer DC: Non-surgical embryo auto-transfer in the mare. Equine vet. J. Suppl. 3, 1985, 100–102.

    Google Scholar 

  • Granstrom E, Kindahi H: Radioimmunoassay of the major plasma metabolite of PGF2a, 15-keto- 13,14-dihydro-PGF2a. Methods Enzymol. 1982, 86, 320–339.

    Article  CAS  Google Scholar 

  • Higgins AJ, Lees P: The acute inflammatory process, arachidonic acid metabolism and the mode of action of antiinflammatory drugs. Equine vet. J. 1984, 16, 163–175.

    Article  CAS  Google Scholar 

  • Kindahi H, Knudsen O, Madej A, Edqvist L-E: Progesterone, prostaglandin F-2a, PMSG and oestrone sulphate during early pregnancy in the mare. J. Reprod. Fert., Suppl. 32, 1982, 353–359.

    Google Scholar 

  • Roberts JS, Barcikowski B, Wilson L, Skarnes RC, McCracken J A: Hormonal and related factors affecting the release of prostaglandin F2a from the uterus. J. Steroid Biochem. 1975, 6, 1091–1097.

    Article  CAS  Google Scholar 

  • Sirois J, Betteridge KJ, Goff AK: PGF-2a release, progesterone secretion and conceptus growth associated with successful and unsuccessful transcervical embryo transfer and reinsertion in the mare. J. Reprod. Fert., Suppl. 35, 1987, 419–427.

    Google Scholar 

  • Squires EL, Cook VM, Voss JL: Collection and transfer of equine embryos. Animal Reproduction Laboratory Bulletin No. 1, 1985, 38 pp.

    Google Scholar 

  • Zarco L, Stabenfeldt GH, Kindahi H, Quirke JF, Granstrom E: Persistence of luteal activity in the non-pregnant ewe. Anim. Reprod. Sci., 1984, 7, 245–267.

    Article  CAS  Google Scholar 

Download references

Acknowledgments

Financial support for this study was provided by the Swedish Council for Forestry and Agricultural Research.

Author information

Authors and Affiliations

  1. Department of Obstetrics and Gynaecology, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, S-75007, Uppsala, Sweden

    K. Kask, L. Malmgren & K. Odensvik

Authors
  1. K. Kask
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. L. Malmgren
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. K. Odensvik
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kask, K., Malmgren, L. & Odensvik, K. Prostaglandin F2α Metabolite Levels Following an Embryo Transfer Procedure in the Mare. Acta Vet Scand 36, 145–147 (1995). https://doi.org/10.1186/BF03547711

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1186/BF03547711

Acta Veterinaria Scandinavica

ISSN: 1751-0147