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Rumen Motility During Induced Hyper- and Hypocalcaemia

Abstract

Rumen motility was recorded on an experimental cow by means of telemetrie signal transfer from strain gauge force transducers fixed surgically on the peritoneal surface of the rumen wall in the left flank. The normocalcaemic cow was given a standard milk fever treatment with calcium borogluconate (400 ml with 14 mg Ca/ml) intravenously. Transient clinical signs were: decreased rumination, muscle ticks, salivation and a heart rate reduction of 20%. Rectal temperature remained unaltered. Frequency of rumen con-tractions was reduced up to 40% whereas amplitude of contractions did not deviate from baseline values. Hypocalcaemia was induced in a second experiment by iv infusion of Na2EDTA. At 0.60 mmol/1 ionized blood calcium periods of no motility were recorded whereas inactivity of rumen activity was persistent at 0.55 mmol/1 ionized blood cal-cium. The cow went down at 0.45-0.48 mmol/1 ionized blood calcium at which point the heart rate was increased by 40%. The high sensitivity of the method employed allowed the conclusion that already at a concentration of ionized blood calcium at 1.0 mmol/1 both frequency and amplitude of rumen contractions decreased rapidly although eating behaviour and rumination appeared unaffected during the short term observation peri-ods. Implications of this finding towards health and production in transition cows are discussed.

References

  • Ballantin HT, Herbein JH: Potentiometrie Determination of Ionized and Total Calcium in Blood Plasma of Holstein and Jersey Cows. J. Dairy Sci. 1992, 74, 446–449.

    Article  Google Scholar 

  • Bowen JM, Blackmon DM, Heavner JE: Neuromuscular transmission and Hypocalcémie Paresis in the Cow. Am. J. Vet. Res. 1970, 31, 831–839.

    CAS  PubMed  Google Scholar 

  • Bueno L, Fioramonti J: Dopaminergic control of gastro-intestinal motility. In: Ruckebusch Y, Toutain P-L & Koritz GD (eds.): Veterinary Pharmacology and Toxicology. AVI Publishing Company, Connecticut, 1983. pp 283–298.

    Chapter  Google Scholar 

  • Daniel RCW: Motility of the Rumen and Abomasum During Hypocalcaemia. Can. J. Comp. Med. 1983, 47, 276–280.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Desmecht DJ-M, Linden AS, Lekeux PM: Ruminai, Cardiorespiratory and Adrenocortical sequelae of Na DTA-induced Hypocalcemia in Calves. Vet. Res. Comm. 1996, 20, 47–60.

    CAS  Article  Google Scholar 

  • Fenvick DC, Daniel RCW: A Comparison Between the Main Clinical Signs of Milk Fever in Cows with Those of Hypocalcaemia Induced by Na DTA Solution. J. Vet. Med. A. 1990, 37, 721–728.

    Article  Google Scholar 

  • Goff JP, Horst RL: Calcium Salts for Treating Hypocalcemia: Carrier Effects, Acid-Base Balance, and Oral Versus Rectal Administration. J. Dairy Sci. 1994, 77, 1451–1456.

    CAS  Article  Google Scholar 

  • Hara S, Tamura T, Takahashi T, Kaneda Y, Tomizawa N, Okada N, Nishida M: Treatment Of Left Displaced Abomasum In Dairy Cows By The Combined Use Of alfa2-Adrenergic Drugs And Rolling. In: Poster Presentations, XIX World Buiatrics Congress, Edinburgh, 1996, Abstract nr. 110.

    Google Scholar 

  • Hove K, Hilde BL: Plasma calcium in the lactating cow: Dependence on continuous intestinal absorption. Can. J. Anim. sci. 1984, Suppl. 64, 227–228.

    Google Scholar 

  • Huber TL, Wilson RC, Stattelman AJ, Goetsch DD: Effect of Hypocalcemia on Motility of the Ruminant Stomach. Am. J. Vet. Res. 1981, 42, 1488–1490.

    CAS  PubMed  Google Scholar 

  • Itoh Z, Honda R, Takeuchi S, Aizawa I, Takayanagi R: An extraluminal force transducer for recording contractile activity of the gastrointestinal smooth muscle in conscious dogs; Its construction and implantation. Gastroent. Jpn. 1977, 12, 275–283.

    CAS  Article  Google Scholar 

  • Kvart C, Bjorsell KA, Larsson L: Parturient paresis in the cow. Acta. vet. scand. 1982, 23, 184–196.

    CAS  Article  Google Scholar 

  • Littledike ET, Glazier D, Cook HM: Electrocardio-graphic Changes After Induced Hypercalcemia and Hypocalcemia in Cattle: Reversal of the Induced Arrhytmia with Atropine. Am. J. Vet. Res. 1976, 37, 383–388.

    CAS  PubMed  Google Scholar 

  • Madison JB, Troutt HF: Effects of hypocalcaemia on abomasal motility. Res. Vet. Sci. 1988, 44, 264–266.

    CAS  Article  Google Scholar 

  • Moreau R, & Squires RA: Hypercalcemia. Compend. Contin. Educ. Prate. Vet. 1992, 14, 1077–1081.

    Google Scholar 

  • Muir LA, Hibbs JW, Conrad HR, Smith KL: Effect Of Estrogen and Progesterone on Feed Intake and Hydroxyproline Excretion Following Induced Hypocalcemia in Dairy Cows. J. Dairy Sci. 1972, 55, 1613–1620.

    CAS  Article  Google Scholar 

  • Navarre CB, Roussel AJ: Gastrointetinal Motility and Diseases in Large Animals. Jour. Vet. Intern. Med. 1996, 20, 51–59.

    Article  Google Scholar 

  • Radostitis OM, Blood DC, Gay CC: Metabolic Diseases. In: Veterinary Medicine; A Textbook of the Diseases of Cattle, Sheep, Pigs, Goats and Horses. Bailliere Tindall, London, 1994 eighth Edition, pp 1310–1367.

    Google Scholar 

  • Rosol TJ, Chew DJ, Nagode LA, Capen CC: Patho-physiology of Calcium Metabolism. Vet. Clin. Patho. 1995, 24, 49–63.

    Article  Google Scholar 

  • Smith VR, Brown WH: Response of some blood constituents to infusions of disodium ethylenediamine tetraacetate in intact cattle. J. Dairy Sci. 1963, 46, 223–226.

    CAS  Article  Google Scholar 

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Acknowledgments

This study was supported by the Danish Agricultural and Veterinary Research Council (grant no. 9600949).

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Correspondence to R. J. Jorgensen.

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Jorgensen, R.J., Nyengaard, N.R., Ham, S. et al. Rumen Motility During Induced Hyper- and Hypocalcaemia. Acta Vet Scand 39, 331–338 (1998). https://doi.org/10.1186/BF03547781

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  • DOI: https://doi.org/10.1186/BF03547781

Keywords

  • ionized blood calcium
  • EDTA-infusion
  • telemetrie measurement