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Plasma Levels of Progesterone and Cortisol after ACTH Administration in Lactating Primiparous Sows

Blodplasmakoncentrationerna av kortisol och progesteron efter ACTH injektion hos lakterande Primipara suggor

Acta Veterinaria Scandinavica volume 39, pages 71–76 (1998)Cite this article

Abstract

The effect of adrenocorticotropic hormone (ACTH) administration on progesterone and Cortisol concentrations was determined in lactating primiparous sows. Physiological saline and 50IU ACTH were administered on days 20 and 21 of lactation at 0900 hours via an indwelling jugular catheter. Blood samples for hormone analysis were collected via indwelling jugular catheters every 15 min (0800 to 1200 hours) and every 60 min (1300 to 1500 hours). Saline administration had no effect on progesterone nor Cortisol concentrations in the lactating sows. Progesterone and Cortisol concentrations increased (p<0.001) within 15 min after ACTH administration. Progesterone and Cortisol concentrations peaked (p<0.01) within 45 min and had returned to pretreatment values within 120 min after ACTH treatment.

Sammanfattning

Effekten av en ACTH injektion på blodplasmakoncentrationerna av kortisol och progesteron bestämdes hos lakterande suggor. Fysiologisk koksaltlösning och 50 IE ACTH injicerades klockan 09.00 på dag 20 respektive dag 21 av laktationen via en permanent inlagd jugularvenkateter. Blodprover för hormonanalyser uppsamlades via venkatetern var 15:e minut under perioden 08.00–12.00 och var 60:e minut under perioden 13.00–15.00. Koksaltinjektionen hade ingen inverkan på vare sig progesteron- eller kortisolkoncentrationerna. Progesteron- och kortisolkoncentrationerna steg (p<0.001) inom 15 minuter efter ACTH-injektionen. Progesteronkoncentrationen var högst (p<0.01) inom 45 minuter och hade återgått till ursprungsvärdena inom 120 min efter ACTH-behandlingen. Den högsta kortisolkoncentrationen uppmätes 45 minuter efter ACTH behandlingen och förhöjda kortisolkoncentrationer (p<0.01) uppmättes under sammanlagt 120 minuter.

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Acknowledgments

This work was supported financially by the Swedish Council for Forestry and Agricultural Research.

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Authors and Affiliations

  1. Department of Obstetrics and Gynaecology, Swedish University of Agricultural Sciences, P.O. Box 7039, S-750 07, Uppsala, Sweden

    V.T. Tsuma & S. Einarsson

  2. Department of Animal Physiology, Swedish University of Agricultural Sciences, Uppsala, Sweden

    A. Madej

  3. Department of Clinical Chemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden

    M. Forsberg

  4. Department of Animal Breeding and Genetics, Centre for Reproductive Biology, Swedish University of Agricultural Sciences, Uppsala, Sweden

    N. Lundeheim

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  1. V.T. Tsuma
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  2. S. Einarsson
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  3. A. Madej
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  4. M. Forsberg
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  5. N. Lundeheim
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Correspondence to V.T. Tsuma.

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Tsuma, V., Einarsson, S., Madej, A. et al. Plasma Levels of Progesterone and Cortisol after ACTH Administration in Lactating Primiparous Sows. Acta Vet Scand 39, 71–76 (1998). https://doi.org/10.1186/BF03547808

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Acta Veterinaria Scandinavica

ISSN: 1751-0147