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Total Serum Protein Levels and Paper Electrophoretic Patterns in Pregnant Ewes

Das totale Serumproteinniveau und das elektrophoretische Bild bei trächtigen Mutterschafen

Total serumproteinmengde og papirelektroforesemønster hos drektige søyer

Summary

Total serum protein levels were determined and filter paper electrophoresis was run in serum samples from 48 ewes during pregnancy under different feeding conditions and anthelmintic treatment.

There was a gradual reduction in total serum protein levels towards lambing in all groups, and also a decrease in the globulin fractions. This caused a rise in A/G from less than 1 to more than 1. After lambing there was a decrease in A/G towards 1, and the fall was most evident in those animals receiving no anthelmintics.

Zusammenfassung

Bei verschiedenen Fütterungsverhältnissen und Anthelmintika-Behandlung wurden in Serumproben von 48 Mutterschafen, die in 4 Gruppen verteilt waren, die totale Proteinmenge während der Trächtigkeit bestimmt. Gleichzeitig wurden dieselben Serumproben mit Hilfe von Papierelektrophorese untersucht.

In allen 4 Gruppen wurden die totale Proteinmenge sowie die Globulin-Fraktionen gegen Ende der Trächtigkeit nach und nach reduziert. Dieses hatte eine Steigerung des Albumin/Globulin-Verhältnisses von unter 1 bis etwas über 1 zur Folge. Nach dem Lammen wurde ein Fall im A/G-Verhältnis gegen 1 beobachtet. Dieses war besonders auffallend bei den Tieren, die nicht Anthelmintika bekommen hatten.

Sammendrag

Under ulike foringsforhold og anthelmintica-behandling ble det i serumprøver fra 48 søyer fordelt på 4 grupper i løpet av drektighetstiden foretatt bestemmelser av total protein mengde. Samtidig ble de samme serumprøver undersøkt ved hjelp av papirelektroforese.

I alle 4 grupper forekom en gradvis reduksjon i total proteinmengde og globulin-fraksjoner henimot lammingstiden. Dette resulterte i en økning i A/G fra under 1 opp til over 1. Etter lamming var det en tendens til fall i A/G henimot 1. Dette var mest påfallende hos de dyr som ikke hadde fått anthelmintica.

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Acknowledgments

I wish to thank Mr. Oddvar Helle, Department of Internal Medicine, Veterinary College of Norway, for his kindness in allowing me to use the nematode egg values, and also Dr. F. W. Jennings, The Wellcome Laboratories for Experimental Parasitology, University of Glasgow, for kind help in reading through the manuscript.

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Hjelle, A. Total Serum Protein Levels and Paper Electrophoretic Patterns in Pregnant Ewes. Acta Vet Scand 8, 273–278 (1967). https://doi.org/10.1186/BF03547832

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