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Ateliotic Dwarfism in the German Shepherd Dog

LOW SOMATOMEDIN ACTIVITY ASSOCIATED WITH APPARENTLY NORMAL PITUITARY FUNCTION (2 CASES) AND WITH PAN-ADENOPITUITARY DYSFUNCTION (1 CASE)

Acta Veterinaria Scandinavica volume 17, pages 293–306 (1976)Cite this article

Abstract

Two types of ateliotic dwarfism in 3 German Shepherd dog puppies are described. Low somatomedin levels in serum and impaired growth of skeletal tissues were found in all 3 cases.

One dog (case 2) had a histologically undeveloped adenohypophysis, and the dwarfism was apparently due to a generalized lack of adenopituitary function.

The 2 other dogs (cases 1A and IB) had histologically normal adenohypophyses, and their condition was probably due to a reduced response to endogenous growth hormone in peripheral tissues.

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Acknowledgments

We are indebted to Associate Professor A. Attramadal, Rikshospitalet (the National Hospital of Norway), and Assistant Professor B. Bratberg, the Department of Pathology, Veterinary College of Norway, for performing the histological sectioning and staining, and for valuable discussions. Thanks are also due to Professor O. Foss, the Oslo City Hospital, Ullevål, for performing the thyroxin-analyses and to Associate Professor K. Halse, the Department of Physiology, Veterinary College of Norway, for the glucose determinations. In addition we wish to thank district veterinary officer R. Gilhuus and veterinary surgeon O. Stenshorne for referring the cases to us. The skilful technical assistance of chem.ing. V. Schuller Jacobsen is gratefully acknowledged.

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  1. Department of Physiology and the Department of Surgery, Veterinary College of Norway, Oslo, Norway

    Tata Ringberg Lund-Larsen & Jorunn Grøndalen

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  1. Tata Ringberg Lund-Larsen
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  2. Jorunn Grøndalen
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Lund-Larsen, T.R., Grøndalen, J. Ateliotic Dwarfism in the German Shepherd Dog. Acta Vet Scand 17, 293–306 (1976). https://doi.org/10.1186/BF03547910

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Acta Veterinaria Scandinavica

ISSN: 1751-0147