- Brief Communication
- Published:
Phosphohexose Isomerase (PHI) and Porcine Halothane Sensitivity
Acta Veterinaria Scandinavica volume 17, pages 370–372 (1976)
Abstract
Malignant hyperthermia is a serious consequence of halo-thane anaesthesia in predisposed animals and humans. In view of the similar clinical-biochemical symptoms in humans as well as in pigs susceptible to halothane anaesthesia, the stress susceptible pig appears to be a useful animal model for study of this abnormal condition and for development of non-destructive detection methods for its identification.
References
Agergaard, N., J. Hyldgaard-Jensen, P. F. Jørgensen, P. B. Nielsen & K. G. S. Olesen: Dansk Landrace 1973. Studier over denne svine-races biokemisk genetiske konstitution. (Danish Landrace 1973. Studies concerning the biochemical genetical constitution of the breed). Kgl. Vet.- og Landbohøjsk., Inst. Sterilitetsforskn., Ârsberetn. 1974, 17, 9–31. København.
Andresen, E.: Close linkage between the locus for phosphohexose iso-merase (PHI) and the H blood group locus in pigs. Anim. Blood Groups Biochem. Genet. 1970, 1, 171–172.
Eikelenboom, G. & D. Minkema: Prediction of pale, soft, exudiative muscle with a non-lethal test for the halothane-induced porcine malignant hyperthermia syndrome. T. Diergeneesk. 1974, 99, 421–426.
Harrison, G. G.: Pale, soft, exudative pore, porcine stress syndrome and malignant hyperpyrexia — an identity. J. S. Afr. vet, med. Ass. 1972, 43, 57–63.
Jensen, P., H. Staun, P. B. Nielsen & J. Moustgaard: Undersøgelser over sammenhsengen mellem blodtyp esy stem H og points for kødfarve hos svin. (Investigations on the relationship between the blood group system H and meat colour in pigs). Medd. Statens Husdyrbrugsforsøg 1976, no. 83.
Rasmusen, B. A. & L. L. Christian: H blood types in pigs as predictors of stress susceptibility. Science 1976, 191, 947–948.
Sybesma, W. & G. Eikelenboom: Malignant hyperthermia syndrome in pigs. Neth. J. Vet. Sci. 1969, 2, 155–160.
Acknowledgment
The authors greatly acknowledge the valuable assistance of Dr. W. A. G. Göp, “Schoonoord”.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Jørgensen, P.F., Hyldgaard-Jensen, J. & Eikelenboom, G. Phosphohexose Isomerase (PHI) and Porcine Halothane Sensitivity. Acta Vet Scand 17, 370–372 (1976). https://doi.org/10.1186/BF03547918
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1186/BF03547918