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Regional Ileitis in Pigs

Morfologiska och patogenetiska synpunkter på regional ileit hos grisar

Morphological and Pathogenetical Aspects

Abstract

Twenty-seven weaned pigs with a wasting appearance were investigated. From a morphological point of view the pigs were divided into three groups. In the group of pigs with macro-scopical signs of regional ileitis, affected tissue showed substantial epithelial proliferation, and electron microscopic studies revealed the presence of microorganisms within the cytoplasm of the epithelial cells. There was a loss of, or only faint, enzymatic activity of alkaline phosphatase in the mucosal epithelium. In another group of five pigs there was no, or only slight, light microscopical signs of regional ileitis but presence of intracellular microorganisms. The enzymatic activity of the ileal epithelium was low. Low enzymatic activity of the ileal epithelium was observed in a third group of wasting pigs, which had no histological or electron microscopical signs of regional ileitis.

Sammanfattning

Författarna har undersökt 27 grisar med typiskt “pelle”-utseende. Ur morfologisk synpunkt indelades de i tre grupper. I gruppen med makroskopiskt påvisbar regional ileit sågs adenomatösa slemhinneproliferationer. Vid elektronmikroskopisk undersökning avslöjades intracytoplasmatiska mikroorganismer i epithelcellerna. Aktiviteten av alkaliskt fosfatas var låg eller saknades helt i slemhinneepithelet. I andra gruppen förekom intracellulär mikroorganismer men endast svaga histologiska tecken på regional ileit. Enzymaktiviteten i epithelcellerna var låg, liksom i tredje gruppen. I sistnämnda grupp förelåg varken ljusmikroskopiska eller elektronmikroskopiska förändringar tydande på regional ileit. Ur patogenetisk synpunkt diskuteras två faktorer som förknippas med sjukdomens uppkomstmekanism. Den ena är predisponerande gastrointestinal rubbning, den andra är intracellulär förekomst av mikroorganismer.

References

  • Biester, H. E. & L. H. Schwarte: Intestinal adenoma in swine. Amer. J. Path. 1931, 7, 175–185.

  • Dodd, D. C.: Adenomatous intestinal hyperplasia (proliferative ileitis) of swine. Path. Vet. 1968, 5, 333–341.

  • Emsbo, P.: Terminal or regional ileitis in swine. Nord. Vet.-Med. 1951, 3, 1–28.

  • Kenworthy, R. & W. D. Allen: The significance of E coli to the young pig. J. comp. Path. 1966, 76, 31–44.

  • Lawson, G. H. K. & A. C. Rowland: Intestinal adenomatosis in the pig: A bacteriological study. Res. Vet. Sci. 1974, 17, 331–336.

  • Martinsson, K. & L. Ekman: Behandlingsförsök med zink avseende s k pellar bland avvanda grisar. (Treatment with zinc on wasting pigs after weaning). Svensk Vet.-Tidn. 1974, 26, 824–828.

  • Martinsson, K. & L. Jonsson: On the mechanism of intestinal absorption of the macromolecules in piglets studied with Dextran Blue. Zbl. Vet.-Med. A 1975, 22, 276–282.

  • Martinsson, K., N. Holmgren, L. Jönsson & G. Nordström: Några undersökningar over terminal ileit hos grisar. (Some observations on terminal ileitis in pigs). Svensk Vet.-Tidn. 1974, 26, 347–354.

  • Moon, H. W.: Epithelial cell migration in the alimentary mucosa of the suckling pig. Proc. Soc. exp. biol. (N.Y.) 1971, 137, 151–154.

  • Moon, H. W.: Vacuolated villous epithelium of the small intestine of young pigs. Vet. Path. 1972, 9, 3–21.

  • Nielsen, K.: Regional enteritis in domestic animals. In Regional Enteritis (Chron’s disease). Ed. by Engel and Larsson, Stockholm 1971.

    Google Scholar 

  • Nielsen, S. W.: Muscular hypertrophy of the ileum in relation to “terminal ileitis” in pigs — a preliminary report. J. Amer. vet. med. Ass. 1955, 127, 437–441.

  • Rahko, T. & H. Saloniemi: On the pathology of regional ileitis in the pig. Nord. Vet.-Med. 1972, 24, 132–138.

  • Rowland, A. C. & G. H. K. Lawson: Intestinal adenomatosis in the pig: Immunofluorescent and electron microscopic studies. Res. Vet. Sci. 1974, 17, 323–330.

  • Rowland, A. C. & G. H. K. Lawson: Intestinal adenomatosis in the pig: A possible relationship with a hemorrhagic enteropathy. Res. Vet. Sci. 1975, 18, 263–268.

  • Rowland, A. C. & P. G. M. Rowntree: A hemorrhagic bowel syndrome associated with intestinal adenomatosis in the pig. Vet. Rec. 1972, 91, 235–241.

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Jönsson, L., Martinsson, Κ. Regional Ileitis in Pigs. Acta Vet Scand 17, 223–232 (1976). https://doi.org/10.1186/BF03547930

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