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Susceptibility of Mink to Clostridium Botulinum Type C Toxin

Summary

Investigations to determine the exact susceptibility of mink to Clostridium botulinum type C toxin clearly showed that mink were considerably less resistant to this toxin than has previously been described. Mink weighing approximately 900 g were killed by 360 MLD when toxin was mixed into the feed. By subcutaneous injection, the lethal dose was determined to be in the range of 18 to 36 MLD.

When comparing the susceptibility per g of body weight after parenteral application of the toxin, mink proved to be less resistant than mice to this type of toxin. Continued feeding tests in mink with suspected material is pointed out as a preferable method for practical demonstrations of Clostridium botulinum type C toxin in cases where the toxin content in the suspected material is very low (1 MLD per g or less).

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Acknowledgment

The authors wish to thank Director of research Arne Helgebostad at the State Experimental Farm for Fur Breeding Animals, Heggedal, for valuable advice and assistance and for providing mink for the experiments.

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Yndestad, M., Loftsgård, G. Susceptibility of Mink to Clostridium Botulinum Type C Toxin. Acta Vet Scand 11, 594–599 (1970). https://doi.org/10.1186/BF03547958

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  • DOI: https://doi.org/10.1186/BF03547958