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Porcine Salmonellosis

Salmonellose hos gris: I. Makroskopiske og mikroskopiske forandringer hos eksperimentelt infiserte dyr

I. Gross and Microscopic Changes in Experimentally Infected Animals

Abstract

Renal vascular lesions associated with experimentally induced septicemic porcine salmonellosis consisted of fibrinoid necrosis of the vessel walls and fibrin thrombi within the lumina of interlobular arteries, afferent arterioles and glomerular capillary loops. Extrarenal vascular alterations were predominantly localized to the skin and the lungs. In these sites, too, mere fibrin thrombi were found in the capillaries, whereas mixed thrombi, consisting of fibrin, platelets, leucocytes and erythrocytes were present in larger vessels. The conclusion is drawn that the renal vascular injury is completely compatible to the generalized Shwartzman reaction, while the extrarenal vascular changes may only in part depend on this mechanism.

Sammendrag

Karskadene i nyrene i forbindelse med eksperimentell septikemisk salmonellose hos gris besto av fibrinoid nekrose av karveggene og fibrintromber i lumina i interlobular-arteriene, i de afferente arterioler og kapillarslyngene i glomeruli. Utenom nyrene ble det i første rekke funnet karforandringer i huden og i lungene. Også i disse lokalisasjonene ble det funnet rene fibrintromber i kapillærene, mens det fantes blandede tromber, som besto av fibrin, blodplater, leukocytter og erythrocytter i de større kar. Det blir konkludert med at karforandringene i nyrene i sin helhet er forenlig med en generalisert Shwartzmans reaksjon, mens de ekstrarenale karforandringene bare delvis kan bero på denne mekanisme.

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Nordstoga, K. Porcine Salmonellosis. Acta Vet Scand 11, 361–369 (1970). https://doi.org/10.1186/BF03547963

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  • DOI: https://doi.org/10.1186/BF03547963