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Porcine Salmonellosis

Salmonellose hos gris: II. Framkallelse au generalisert Shwartzmans reaksjon ved intravenøse injeksjoner av knuste celler av Salmonella cholerae-suis

II. Production of the Generalized Shwartzman Reaction by Intravenous Injections of Disintegrated Cells of Salmonella Cholerae-Suis

Abstract

Three pigs were given intravenous injections of disintegrated cells of Salmonella cholerae-suis. One of these pigs developed macroscopic bilateral renal cortical necrosis. Histologic examination revealed, besides total cortical parenchymal necrosis, also severe vascular injury, characterized with fibrinoid necrosis of the vessel walls and fibrin thrombi within their lumina. These findings were interpreted as a result of a generalized Shwartzman reaction, provoked by the action of bacterial endotoxin.

Sammendrag

Tre griser ble gitt knuste Salmonella cholerae-suis bakterier intravenøst. En av disse grisene utviklet makroskopisk bilateral nyrebarknekrose. Histologisk undersøkelse viste, foruten total nekrose av nyre-barken, også utbredt karskade karakterisert ved fibrinoid nekrose av karveggene og fibrintromber i lumina. Disse funn ble tolket som resultat av en generalisert Shwartzmans reaksjon, utløst gjennom virkningen av bakterielle endotoksiner.

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Nordstoga, K., Fjölstad, M. Porcine Salmonellosis. Acta Vet Scand 11, 370–379 (1970). https://doi.org/10.1186/BF03547964

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  • DOI: https://doi.org/10.1186/BF03547964