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Individual Variation in Blood Magnesium and Susceptibility to Hypomagnesaemia in Cows
Individuelle variasjoner i blodmagnesium og hypomagnesemi-tilbøye-lighet hos kyr
Acta Veterinaria Scandinavica volume 11, pages 394–414 (1970)
Abstract
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1.
Within a normal range for blood magnesium in cows, 1.55-3.0 mg of Mg per 100 ml of serum or plasma, statistically significant differences between individuals were detected.
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2.
Reference was made to studies of the renal handling of magnesium and to demonstrations in the literature of large individual variations in the ability of cows to utilize magnesium from the diet. It is logical to assume that such variations will contribute to the creation of individual differences in plasma levels of the element. The point was emphasized that to moderate differences in plasma concentration can correspond large quantitative differences in magnesium metabolism.
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3.
A positive correlation was demonstrated in one herd between earlier individual plasma magnesium levels within the normal range and decreased levels after one week on a tetany-producing pasture.
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4.
Gows with initial plasma magnesium values in the lower part of the range of a group of animals appeared specially susceptible to disease when subsequently the whole group was subjected to hypo- magnesaemia-producing conditions. This rule was detected within the limited material from the mentioned herd with tetany and also in materials from the literature.
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5.
The possibility that certain individuals within herds can be pointed out as specially susceptible to hypomagnesaemic disturbances before the beginning of a tetany season may be of practical interest.
Sammendrag
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1.
Innen et normalt variasjonsområde for blodmagnesium hos kyr, 1,55—3,0 mg Mg/lO0 ml serum eller plasma, ble det funnet statistisk signifikante forskjeller mellom individer.
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2.
I diskusjonen ble det henvist til studier over magnesiumtransporten i nyrene og til litteraturkilder som viser store individuelle variasjoner hos kyr i evnen til å utnytte magnesium fra foret. Det er å vente at slike variasjoner vil bidra til framkomsten av individuelle nivåforskjeller for magnesium i blodplasma. Det ble særlig understreket at det til moderate forskjeller i plasma konsentrasjon kan svare store kvantitative forskjeller i magnesiumstoffskiftet.
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3.
En positiv korrelasjon ble påvist i en besetning mellom tidligere observerte individuelle plasma magnesiumnivåer innen et normalt variasjonsområde og nedsatte nivåer etter en uke på et tetaniframkallende beite.
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4.
Kyr med utgangsverdier for plasmamagnesium i den lavere del av variasjonsområdet for en gruppe av dyr viste spesielt stor tilbøyelighet til sykdom når hele gruppen etterpå ble utsatt for hypomag-nesemiframkallende påkjenninger. Denne regelen ble påvist i det begrensede materialet fra tetanibesetningen nevnt ovenfor og i observasjonsmaterialer fra litteraturen.
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5.
Muligheten av å peke ut innen besetninger før begynnelsen av en tetanisesong kyr med spesiell tilbøyelighet til hypomagnesemiske forstyrrelser antas å være av praktisk interesse.
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Halse, K. Individual Variation in Blood Magnesium and Susceptibility to Hypomagnesaemia in Cows. Acta Vet Scand 11, 394–414 (1970). https://doi.org/10.1186/BF03547967
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DOI: https://doi.org/10.1186/BF03547967