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Diurnal and Individual Variations in Bile Acids in the Plasma of Normal Dairy Cows

Acta Veterinaria Scandinavica volume 30, pages 221–228 (1989)Cite this article

Abstract

Blood samples were collected every 2 h during a 24 h period from 6 cows of one herd and 10 cows of another herd. In a third herd 9 cows were sampled every 2 h from 6 a.m. to 8 p.m. Concentrations of total bile acids, acetoacetate, glucose and free fatty acids were determined in blood plasma.

A marked difference in individual bile acid concentrations and patterns of diurnal variation was found. For most cows the highest bile acid values were observed between 2 and 6 a.m. (overall mean (± SD) at 6 a.m.: 104 ± 84 µmol/1, range: 20-307 µmol/1). Fourteen cows with a bile acid value > 90 µmol/1 at 6 a.m. (”high BA”) were characterized as a group by showing a pronounced decrease in the mean bile acid concentration after morning feeding. In the group of 11 cows with a 6 a.m. bile acid value < 90 µmol/1 (”low BA”) the time of day did not contribute significantly to the bile acid variation.

For the” high BA” group a nearly synchronous variation between the mean values of the 3 feeding dependent parameters (acetoacetate, glucose and free fatty acids) and the mean values of bile acids was found. The within animal coefficients of correlation between bile acids and the feeding dependent parameters were significantly higher in the” high BA” group than in the” low BA” group.

No direct connection was found between bile acid levels and the quantity of concentrates fed or the individual milk yield.

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Authors and Affiliations

  1. Department of Biochemistry and Department of Reproductive Physiology and Pathology, Norwegian College of Veterinary Medicine, P. O. Box 8146, Dep., N-0033 Oslo 1, Oslo, Norway

    Signe Videm Abdelkader & Erik Ropstad

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  1. Signe Videm Abdelkader
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  2. Erik Ropstad
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Abdelkader, S.V., Ropstad, E. Diurnal and Individual Variations in Bile Acids in the Plasma of Normal Dairy Cows. Acta Vet Scand 30, 221–228 (1989). https://doi.org/10.1186/BF03548058

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  • DOI: https://doi.org/10.1186/BF03548058

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Acta Veterinaria Scandinavica

ISSN: 1751-0147