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Comparative Effect of Selenium in Wheat, Barley, Fish Meal and Sodium Selenite for Prevention of Exudative Diathesis in Chicks

Komparativ effekt av selen i vete, korn, fiskmjöl och natriumselenit vid förebyggandet av exudativ diates i kycklingar

Acta Veterinaria Scandinavica volume 27, pages 461–478 (1986)Cite this article

Abstract

Groups af White Leghorn chicks obtained from dams deprived on selenium (Se), were fed from hatching a low-Se-vitamin E basal diet alone, or supplemented with 0.02, 0.04, 0.06 or 0.08 mg Se/kg diet, as sodium selenite (Na2SeO3 · 5H2O), wheat, barley or fish meal. Prevention of the Se-vitamin E deficiency responsive disease exudative diathesis (ED) as it was clinical observed, induction of the plasma Se dependent enzyme glutathione peroxidase (GSH-Px) activity, and Se concentration in the cardiac muscle were observed to be dietary Se level and source dependent. Slope ratio assay was applied to estimate the biological availability of Se in the natural sources relative to Se in sodium selenite. For the prevention of ED, the bioavailability of Se in wheat, barley and fish meal was 99, 85 and 80 %, respectively. The increase in the plasma GSH-Px activity revealed a bioavailability for Se in wheat, barley and fish meal of 79, 71 and 66 %, respectively. Using retention of Se in the cardiac muscle as the bioassay, a bioavailability of 108, 87 and 100 % was calculated for wheat, barley and fish meal Se, respectively.

Sammanfattning

Vita Leghornky eklinga r efter höns utarmade på selen utfodrades från kläckning gruppvis enbart med en selen- och E-vitaminfattig basaldiet eller basaldieten sopplementerad med 0.02, 0.04, 0.06 eller 0.08 mg selen/kg foder som natriumselenit, vete, korn eller fiskmjöl. Förebyggandet av kliniska symptom till den av selen-E-vitaminbrist beroende sjukdomen exudativ diates (ED), induceringen av aktiviteten av selenberoende enzymet glutation peroxidas i plasma och koncentrationen av selen i hjärtmuskeln konstaterades vara beroende både pä mängden dietärt tillfört selen och på arten av selenkälla. Lineär regressionsanalys användes för att uppskatta selenets biologiska tillgänglighet i de naturliga fodermedlen jämfört med den för natriumselenit.

Vid förebyggandet av exudativ diates var den biologiska tillgängligheten av selen 99 % i vete, 85 % i korn och 80 % i fiskmjöl. Induceringen av plasma glutation peroxidasaktiviteten avslöjade en biologisk tillgänglighet av selen på 79 % i vete, 71 % i korn och 55 % i fiskmjöl. Användningen av selen re tention i hjärtmuskeln som biologiskt mått för selenets biologiska tillgänglighet gav som motsvarande siffror 108 % för vete, 87 % för korn och 100 % för fiskmjöl.

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Acknowledgments

The author wishes to thank professor Juhani Hakkarainen, Department of Clinical Nutrition, College of Veterinary Medicine, Uppsala, Sweden, and professor Paul Lindberg, Department of Biochemistry, College of Veterinary Medicine, Helsinki, Finland, for their help and advice while conducting this investigation. The generous supply of selenium enriched wheat and barley by Ph.D. Johan Korkman, and Kemira Oy, Helsinki, Finland, and herring fish meal by Dir. Bertil österbo, Västkustfisk AB, Gothenburg, Sweden is gratefully acknowledged. Thanks are due to M.Sc. Birgitta Vegerfors-Persson and Ph.D. Gunnar Ekbohm, the Department of Economics and Statistics, College of Agricultural Sciences, Uppsala, Sweden, for performing the statistical analyses. This investigation was supported by grants from the Swedish Council for Forestry and Agricultural Research.

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  1. Department of Clinical Nutrition, College of Veterinary Medicine, Swedish University of Agricultural Sciences, P. O. Box 7023, S-750 07, Uppsala, Sweden

    Saifeldin Hassan

  2. Department of Biochemistry, College of Veterinary Medicine, Helsinki, Finland

    Saifeldin Hassan

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Hassan, S. Comparative Effect of Selenium in Wheat, Barley, Fish Meal and Sodium Selenite for Prevention of Exudative Diathesis in Chicks. Acta Vet Scand 27, 461–478 (1986). https://doi.org/10.1186/BF03548126

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