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Corynebacterium Pseudotuberculosis Infection in Goats III.

Corynebacterium pseudotuberculosis infeksjon hos geit III. Relasjon til alder

The Influence of Age

Abstract

Serological examinations for Gorynebacterium pseudotuberculosis in-fection were carried out in 14 known positive herds and in 1 herd that had beeni recently established through purchase of animals from different herds. Serum samples were collected sequentially on up to 4 occasions from animals during their first year of life. In most herds, these animals were examined clinically for superficial swellings once or twice during the same period.

The adult goats in 8 infected herds were examined both clinically and serologically. Age distribution was similar in each of these herds. All serum samples were examined for antibodies against Gorynebac-terium pseudotuberculosis in both the bacterial agglutination test (BAT) and the hemolysis inhibition test (HIT).

The proportion of kids which were seropositive in both tests de-creased to zero at 4 months of age. At the age of 11–12 months, the proportion of seropositive animals was about 50 % in the BAT and 30 % in the HIT.

When examined when housed for the winter at the age of about 8 months (mean age), the prevalence of animals with superficial swellings was 7 %. At the age of about 1 year (mean age), 29 % of the examined animals had such lesions. In the recently established herd, only a few of the yearlings were seropositive.

Titre values in BAT and HIT increased until 6 years of age. Anti-body titre values were significantly lower in yearlings than in older goats in both tests, P < 0.005. No significant difference in the propor-tion of goats with superficial swellings was seen at the different ages.

Sammendrag

I 14 besetninger med kaseøs lymfadenitt og i 1 nyetablert besetning med kje innkjøpt fra ulike besetninger ble dyrene undersøkt serologisk inntil 4 ganger til de var ca. ett år gamle. Kliniske undersøkelser ble foretatt av disse dyrene 1 eller 2 ganger i de fleste besetningene i samme periode.

I 8 besetninger med kaseøs lymfadenitt ble det dessuten foretatt kliniske og serologiske undersøkelser av voksne geiter av forskjellig alder. Aldersfordelingen til dyrene i disse besetningene var tilnærmet lik.

Sera ble undersøkt for antistoffer mot Corynebacterium pseudotuberculosis både ved bakterieagglutinasjonstest (BAT) og antihemolysintest (AHT).

Prevalensen av kje positive ved BAT og AHT avtok til null i løpet av de 4 første levemåneder. Ved 11–12 måneders alder var andelen positive dyr økt til 50 % ved BAT og 30 % ved AHT. Prevalensen av dyr med overfladiske hevelser var 7 % når dyrene var ca. 8 måneder gamle (gjennomsnittlig) ved innsetting om høsten. Ved ca. 1 års alder (gjennomsnittlig) hadde 29 % av de undersøkte dyrene slike lesjoner.

I den nyetablerte besetningern var få dyr serologisk positive ved 1 års alderen.

Titeret ved BAT og AHT økte fra 1 til 6 års alder. Ett år gamle geiter hadde signifikant lavere titer ved begge testene enn eldre geiter, P < 0,005. Det var ingen signifikant forskjell i prevalensen av geiter med overfladiske hevelser i de ulike aldersgrupper fra og med 1 års alder.

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Holstad, G. Corynebacterium Pseudotuberculosis Infection in Goats III.. Acta Vet Scand 27, 598–608 (1986). https://doi.org/10.1186/BF03548139

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